ArticleRadiology2017
Prevalence of Fatty Liver Disease and Hepatic Iron Overload in a Northeastern German Population by Using Quantitative MR Imaging.
Open access · greenAbstract read
In one paragraph
Article in Radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 123 citations in OpenAlex.
- Trial
- Sex- and age-specific associations between body composition markers and estimated glomerular filtration rate-results of a population-based study.Clinical kidney journal · 2026Article
- Genetically Determined Loss-of-Function of the Organic Cation Transporter OCT1 Is Associated with Lower Liver Fat Content in Humans.International journal of molecular sciences · 2026Article
- Age-related changes in adiposity and cardiometabolic disease risk: a longitudinal and prospective study in the UK Biobank.International journal of obesity (2005) · 2026Article
- The impacts of time of echo and time of repetition on slow diffusion coefficient (SDC) measure and the potential age- and gender-related variations in liver and spleen SDC values: studies of healthy volunteers.Quantitative imaging in medicine and surgery · 2026Article
- Clinical assessment of hepatic steatosis and iron content using three-dimensional (3D) multi-echo chemical shift encoded magnetic resonance imaging (MRI): correlation with histopathology.Quantitative imaging in medicine and surgery · 2026Article
- Evaluation of 0.55T MRI for Simultaneous R2* and Fat Fraction Quantification in the Presence of Hepatic Iron Overload and Steatosis Using Simulations and Phantoms.Magnetic resonance in medicine · 2026Article
- Spatial characterization of intrahepatic fat deposition across steatotic liver disease subcategories: a multicenter study.BMC medicine · 2026Article
- Mildly elevated liver lipid content is characterised by reduced insulin sensitivity.JHEP reports : innovation in hepatology · 2025Article
- A framework of biomarkers for adipose tissue aging: a consensus statement by the Aging Biomarker Consortium.Life medicine · 2025Article
- Multi-Center, Multi-Vendor Validation of Simultaneous MRI-Based Proton Density Fat Fraction and R2* Mapping Using a Combined Proton Density Fat Fraction-R2* Phantom.Journal of magnetic resonance imaging : JMRI · 2025Article
- MR and Ultrasound for Liver Fat Assessment in Children: Techniques and Supporting Evidence.Journal of magnetic resonance imaging : JMRI · 2025Review
- Serum metabolites characterize hepatic phenotypes and reveal shared pathways: results from population-based imaging.Molecular medicine (Cambridge, Mass.) · 2025Article
- Biochemical, sex hormonal, and anthropometric predictors of non-alcoholic fatty liver disease in polycystic ovary syndrome.BMC women's health · 2025Article
- Comprehensive assessment of distinct abdominal fat compartments beyond liver content in overweight/obese patients using MRI and ultrasound imaging.Abdominal radiology (New York) · 2025Article
- Nonlinear Association Between the Liver Fat Content and the Risk of Hyperuricemia in Prediabetic Individuals: Evidence from Cross-Sectional Health Screening Data in China.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Evaluating the efficacy of 8 non-invasive models in predicting MASLD and progression: a prospective study.BMC gastroenterology · 2024Article
- Exploring factors associated with non-alcoholic fatty liver disease using longitudinal MRI.BMC gastroenterology · 2024Article
- Alisma Orientalis Extract Ameliorates Hepatic Iron Deregulation in MAFLD Mice via FXR-Mediated Gene Repression.Nutrients · 2024Article
- Lower muscular strength is associated with greater liver fat content and higher serum liver enzymes-"The Sedentary's Liver" The Study of Health in Pomerania.European journal of sport science · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Jens-Peter KühnFrom the Institute of Diagnostic Radiology and Neuroradiology (J.P.K., C.H., M.L.K., C.O.S., B.M.), Institute for Community Medicine (P.M., H.V.), and Department of Medicine A, University Medicine (M.M.L., J.M.), Ernst Moritz Arndt University Greifswald, Berthold-Beitz-Platz, 17495 Greifswald, Germany; Department of Radiology, University of Wisconsin, Madison, Wis (D.H., S.B.R.); and Department of Medical Physics, Biomedical Engineering, Medicine and Emergency Medicine, University of Wisconsin, Madison, Wis (S.B.R.).
Peter MeffertFrom the Institute of Diagnostic Radiology and Neuroradiology (J.P.K., C.H., M.L.K., C.O.S., B.M.), Institute for Community Medicine (P.M., H.V.), and Department of Medicine A, University Medicine (M.M.L., J.M.), Ernst Moritz Arndt University Greifswald, Berthold-Beitz-Platz, 17495 Greifswald, Germany; Department of Radiology, University of Wisconsin, Madison, Wis (D.H., S.B.R.); and Department of Medical Physics, Biomedical Engineering, Medicine and Emergency Medicine, University of Wisconsin, Madison, Wis (S.B.R.).
Christian HeskeFrom the Institute of Diagnostic Radiology and Neuroradiology (J.P.K., C.H., M.L.K., C.O.S., B.M.), Institute for Community Medicine (P.M., H.V.), and Department of Medicine A, University Medicine (M.M.L., J.M.), Ernst Moritz Arndt University Greifswald, Berthold-Beitz-Platz, 17495 Greifswald, Germany; Department of Radiology, University of Wisconsin, Madison, Wis (D.H., S.B.R.); and Department of Medical Physics, Biomedical Engineering, Medicine and Emergency Medicine, University of Wisconsin, Madison, Wis (S.B.R.).
Marie-Luise KromreyFrom the Institute of Diagnostic Radiology and Neuroradiology (J.P.K., C.H., M.L.K., C.O.S., B.M.), Institute for Community Medicine (P.M., H.V.), and Department of Medicine A, University Medicine (M.M.L., J.M.), Ernst Moritz Arndt University Greifswald, Berthold-Beitz-Platz, 17495 Greifswald, Germany; Department of Radiology, University of Wisconsin, Madison, Wis (D.H., S.B.R.); and Department of Medical Physics, Biomedical Engineering, Medicine and Emergency Medicine, University of Wisconsin, Madison, Wis (S.B.R.).
Carsten O SchmidtFrom the Institute of Diagnostic Radiology and Neuroradiology (J.P.K., C.H., M.L.K., C.O.S., B.M.), Institute for Community Medicine (P.M., H.V.), and Department of Medicine A, University Medicine (M.M.L., J.M.), Ernst Moritz Arndt University Greifswald, Berthold-Beitz-Platz, 17495 Greifswald, Germany; Department of Radiology, University of Wisconsin, Madison, Wis (D.H., S.B.R.); and Department of Medical Physics, Biomedical Engineering, Medicine and Emergency Medicine, University of Wisconsin, Madison, Wis (S.B.R.).
Birger MenselFrom the Institute of Diagnostic Radiology and Neuroradiology (J.P.K., C.H., M.L.K., C.O.S., B.M.), Institute for Community Medicine (P.M., H.V.), and Department of Medicine A, University Medicine (M.M.L., J.M.), Ernst Moritz Arndt University Greifswald, Berthold-Beitz-Platz, 17495 Greifswald, Germany; Department of Radiology, University of Wisconsin, Madison, Wis (D.H., S.B.R.); and Department of Medical Physics, Biomedical Engineering, Medicine and Emergency Medicine, University of Wisconsin, Madison, Wis (S.B.R.).
Henry VölzkeFrom the Institute of Diagnostic Radiology and Neuroradiology (J.P.K., C.H., M.L.K., C.O.S., B.M.), Institute for Community Medicine (P.M., H.V.), and Department of Medicine A, University Medicine (M.M.L., J.M.), Ernst Moritz Arndt University Greifswald, Berthold-Beitz-Platz, 17495 Greifswald, Germany; Department of Radiology, University of Wisconsin, Madison, Wis (D.H., S.B.R.); and Department of Medical Physics, Biomedical Engineering, Medicine and Emergency Medicine, University of Wisconsin, Madison, Wis (S.B.R.).
Markus M LerchFrom the Institute of Diagnostic Radiology and Neuroradiology (J.P.K., C.H., M.L.K., C.O.S., B.M.), Institute for Community Medicine (P.M., H.V.), and Department of Medicine A, University Medicine (M.M.L., J.M.), Ernst Moritz Arndt University Greifswald, Berthold-Beitz-Platz, 17495 Greifswald, Germany; Department of Radiology, University of Wisconsin, Madison, Wis (D.H., S.B.R.); and Department of Medical Physics, Biomedical Engineering, Medicine and Emergency Medicine, University of Wisconsin, Madison, Wis (S.B.R.).
Diego HernandoFrom the Institute of Diagnostic Radiology and Neuroradiology (J.P.K., C.H., M.L.K., C.O.S., B.M.), Institute for Community Medicine (P.M., H.V.), and Department of Medicine A, University Medicine (M.M.L., J.M.), Ernst Moritz Arndt University Greifswald, Berthold-Beitz-Platz, 17495 Greifswald, Germany; Department of Radiology, University of Wisconsin, Madison, Wis (D.H., S.B.R.); and Department of Medical Physics, Biomedical Engineering, Medicine and Emergency Medicine, University of Wisconsin, Madison, Wis (S.B.R.).
Julia MayerleFrom the Institute of Diagnostic Radiology and Neuroradiology (J.P.K., C.H., M.L.K., C.O.S., B.M.), Institute for Community Medicine (P.M., H.V.), and Department of Medicine A, University Medicine (M.M.L., J.M.), Ernst Moritz Arndt University Greifswald, Berthold-Beitz-Platz, 17495 Greifswald, Germany; Department of Radiology, University of Wisconsin, Madison, Wis (D.H., S.B.R.); and Department of Medical Physics, Biomedical Engineering, Medicine and Emergency Medicine, University of Wisconsin, Madison, Wis (S.B.R.).
Scott B ReederFrom the Institute of Diagnostic Radiology and Neuroradiology (J.P.K., C.H., M.L.K., C.O.S., B.M.), Institute for Community Medicine (P.M., H.V.), and Department of Medicine A, University Medicine (M.M.L., J.M.), Ernst Moritz Arndt University Greifswald, Berthold-Beitz-Platz, 17495 Greifswald, Germany; Department of Radiology, University of Wisconsin, Madison, Wis (D.H., S.B.R.); and Department of Medical Physics, Biomedical Engineering, Medicine and Emergency Medicine, University of Wisconsin, Madison, Wis (S.B.R.).
University of Wisconsin–Madison · US
Funding
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2MTechnical Validation of MRI Biomarkers of Liver FatR01DK088925 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI REEDER, SCOTT B., SIRLIN, CLAUDE B · 2010 to 2021
$7.1MConfounder-Corrected Quantitative MRI Biomarkers of HepaticR01DK100651 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI REEDER, SCOTT B. · 2014 to 2017
$2.7MTechnical Development of Quantitative Biomarkers of Fatty Liver Disease with MRIR01DK083380 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI REEDER, SCOTT B. · 2010 to 2013
$1.2MEvolution of Quantitative MRI Biomarkers of Metabolic Syndrome During PubertyK24DK102595 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI REEDER, SCOTT B. · 2014 to 2018
$927kNCATS NIH HHS UL1 TR000427NIDDK NIH HHS K24 DK102595NIDDK NIH HHS R01 DK083380NIDDK NIH HHS R01 DK088925NIDDK NIH HHS R01 DK100651
Abstract
Purpose To quantify liver fat and liver iron content by measurement of confounder-corrected proton density fat fraction (PDFF) and R2* and to identify clinical associations for fatty liver disease and liver iron overload and their prevalence in a large-scale population-based study. Materials and Methods From 2008 to 2013, 2561 white participants (1336 women; median age, 52 years; 25th and 75th quartiles, 42 and 62 years) were prospectively recruited to the Study of Health in Pomerania (SHIP). Complex chemical shift-encoded magnetic resonance (MR) examination of the liver was performed, from which PDFF and R2* were assessed. On the basis of previous histopathologic calibration, participants were stratified according to their liver fat and iron content as follows: none (PDFF, ≤5.1%; R2*, ≤41.0 sec
Indexed as
AdultCross-Sectional StudiesFemaleGermanyHumansImage Interpretation, Computer-AssistedIron OverloadLiverMagnetic Resonance ImagingMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseProspective Studies
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.