Evidence map›Paper›PMID 28481037›Full record

ArticleNMR in biomedicine2017

Regional quantification of myocardial mechanics in rat using 3D cine DENSE cardiovascular magnetic resonance.

Xiaoyan Zhang, Zhan-Qiu Liu, Dara Singh, Gregory J Wehner, David K Powell, Kenneth S Campbell, Brandon K Fornwalt, Jonathan F Wenk

Abstract read
In one paragraph

Article in NMR in biomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoyan ZhangDepartment of Mechanical Engineering, University of Kentucky, Lexington, KY, USA.
Zhan-Qiu LiuDepartment of Mechanical Engineering, University of Kentucky, Lexington, KY, USA.
Dara SinghDepartment of Mechanical Engineering, University of Kentucky, Lexington, KY, USA.
Gregory J WehnerDepartment of Biomedical Engineering, University of Kentucky, Lexington, KY, USA.
David K PowellDepartment of Anatomy and Neurobiology, University of Kentucky, Lexington, KY, USA.
Kenneth S CampbellDepartment of Physiology, University of Kentucky, Lexington, KY, USA.
Brandon K FornwaltDepartment of Biomedical Engineering, University of Kentucky, Lexington, KY, USA.
Jonathan F WenkDepartment of Mechanical Engineering, University of Kentucky, Lexington, KY, USA.ORCID http://orcid.org/0000-0003-0272-9914

Funding

The role of IKKß in linking obesity to adipose tissue inflammation and adipogeneP20GM103527 · NIGMS · UNIVERSITY OF KENTUCKY · PI CASSIS, LISA A · 2012 to 2017
$13.7M
Kentucky Center for Clinical and Translational ScienceUL1TR000117 · NCATS · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2012 to 2015
$13.3M
A High-Field Small Animal MR Imager for Biomedical ResearchS10RR029541 · NCRR · UNIVERSITY OF KENTUCKY · PI SMITH, CHARLES DENNIS · 2010 to 2010
$3.1M
NCATS NIH HHS UL1 TR000117NCRR NIH HHS S10 RR029541NIGMS NIH HHS P20 GM103527
6 · The paper itself

Abstract

Rat models have assumed an increasingly important role in cardiac research. However, a detailed profile of regional cardiac mechanics, such as strains and torsion, is lacking for rats. We hypothesized that healthy rat left ventricles (LVs) exhibit regional differences in cardiac mechanics, which are part of normal function. In this study, images of the LV were obtained with 3D cine displacement encoding with stimulated echoes (DENSE) cardiovascular magnetic resonance in 10 healthy rats. To evaluate regional cardiac mechanics, the LV was divided into basal, mid-ventricular, and apical regions. The myocardium at the mid-LV was further partitioned into four wall segments (i.e. septal, inferior, lateral, and anterior) and three transmural layers (i.e. sub-endocardium, mid-myocardium, and sub-epicardium). The six Lagrangian strain components (i.e. E

Indexed as

Imaging, Three-DimensionalMagnetic Resonance Imaging, CineAnimalsBiomechanical PhenomenaFemaleHeart VentriclesMesothelinMyocardiumRats, Sprague-DawleyReproducibility of ResultsSystoleTorsion, MechanicalMesothelin3D cine DENSE CMRratstraintorsion

Identifiers

PMID28481037
PMCPMC10539034

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.