Evidence map›Paper›PMID 28480752›Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis2018

The Evaluation of D-Dimer Levels for the Comparison of Fibrinogen and Fibrin Units Using Different D-Dimer Kits to Diagnose VTE.

Masahiro Hasegawa, Hideo Wada, Toshio Yamaguchi, Hiroki Wakabayashi, Naoki Fujimoto, Takeshi Matsumoto, Kei Hasegawa, Norikazu Yamada, Masaaki Ito, Yoshiki Yamashita and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Congenital Thrombophilia in Patients With Superior Mesenteric Venous Thrombosis or Portal Vein Thrombosis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Masahiro Hasegawa1 Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Hideo Wada2 Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
Toshio Yamaguchi1 Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Hiroki Wakabayashi1 Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Naoki Fujimoto2 Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
Takeshi Matsumoto3 Department of Blood Transfusion, Mie University Graduate School of Medicine, Tsu, Japan.
Kei Hasegawa4 Central Laboratory, Mie University Graduate School of Medicine, Tsu, Japan.
Norikazu Yamada5 Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Japan.
Masaaki Ito5 Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Japan.
Yoshiki Yamashita6 Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu, Japan.
Naoyuki Katayama6 Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu, Japan.
Kaname Nakatani4 Central Laboratory, Mie University Graduate School of Medicine, Tsu, Japan.
Akihiro Sudo1 Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Mie University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cutoff values of D-dimer levels for diagnosing or predicting the occurrence of deep vein thrombosis (DVT) were evaluated in preoperative patients and compared to those in non-DVT patients. The levels of 8 different D-dimers were measured using the latex agglutination method or enzyme immunoassay before surgery in 262 orthopedic surgery patients to diagnose subclinical DVT or predict postoperative DVT. There were 15 patients with subclinical DVT and 47 with postoperative DVT, but 200 patients had no DVT at all. All 8 plasma D-dimer values were significantly higher in the patients with subclinical or postoperative DVT than in those without DVT or in healthy volunteers. There were differences in the cutoff values between the assays highly sensitive for low D-dimer levels and wild-range assays of D-dimers. Some D-dimer assays might therefore be more useful than others for diagnosing low levels of D-dimer. Although the measurement of D-dimer levels was useful for diagnosing subclinical DVT and predicting the risk of DVT, the cutoff values for the diagnosis or prediction of DVT varied. The cutoff values for the prediction of postoperative DVT were ≥1.7 µg/mL (D-dimer A-D) and ≥1.0 µg/mL (D-dimer E-H).

Indexed as

AgedFemaleFibrinFibrin Fibrinogen Degradation ProductsFibrinogenHumansMaleMiddle AgedPulmonary EmbolismVenous ThrombosisFibrinFibrin Fibrinogen Degradation Productsfibrin fragment DFibrinogencutoff valueD-dimerDVTorthopedic surgery

Identifiers

PMID28480752
PMCPMC6714702
OpenAlexW2612401379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.