Evidence map›Paper›PMID 28480653›Full record

ArticleJournal of Korean medical science2017

The Rate of Drug-Resistant Tuberculosis in Korean Children and Adolescents Since 2007.

Hyun Jung Kim, Hyung Ho Yoon, Byung Wook Eun, Youngmin Ahn, Sungweon Ryoo, Hee Jin Kim

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hyun Jung KimDepartment of Pediatrics, Eulji General Hospital, Eulji University, Seoul, Korea.ORCID http://orcid.org/0000-0001-6103-6961
Hyung Ho YoonDepartment of Pediatrics, Eulji General Hospital, Eulji University, Seoul, Korea.ORCID http://orcid.org/0000-0001-5703-8577
Byung Wook EunDepartment of Pediatrics, Eulji General Hospital, Eulji University, Seoul, Korea.ORCID http://orcid.org/0000-0003-3147-9061
Youngmin AhnDepartment of Pediatrics, Eulji General Hospital, Eulji University, Seoul, Korea.ORCID http://orcid.org/0000-0002-1697-8041
Sungweon RyooKorean National Tuberculosis Association, Seoul, Korea.ORCID http://orcid.org/0000-0002-5085-0068
Hee Jin KimThe Korean Institute of Tuberculosis, Cheongju, Korea.ORCID http://orcid.org/0000-0002-0128-2789
Eulji University · KRKorea National Tuberculosis Association · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of drug-resistant tuberculosis (DR-TB) in pediatric populations is a critical indicator of national TB management and treatment strategies. Limited data exist regarding the rate of pediatric DR-TB. In this study, we aimed to analyze the status of DR-TB in Korean children from 2007 to 2013. We analyzed specimens submitted to the Korean Institute of Tuberculosis using Mycobacterium tuberculosis culture and drug susceptibility tests (DSTs) from January 2007 through December 2013. Specimens from patients ≤ 19 years of age were included. Among the 2,690 cases, 297 cases were excluded because of insufficient data, leaving 2,393 cases for the final analysis. In total, resistance to one or more TB drugs was 13.5%. The resistance rates of each of the drugs were as follows: isoniazid (INH) 10.2%, rifampin (RFP) 5.1%, ethambutol (EMB) 3.7%, and pyrazinamide (PZA) 3.1%. The resistance rate of multidrug-resistant TB (MDR-TB) was 4.2%, and that of extensively drug-resistant TB (XDR-TB) was 0.8%. The overall drug resistance rate demonstrated significant increase throughout the study period (P < 0.001) but showed no significant difference compared to previous study from 1999 to 2007. The drug resistance rate of PZA in ≤ 15 years of age group was significantly greater than that of > 15 years (P < 0.001). The drug resistance rate has increased throughout the study period.

Indexed as

AdolescentAntitubercular AgentsAsian PeopleChildChild, PreschoolDrug Resistance, Multiple, BacterialEthambutolFemaleHumansIncidenceInfantIsoniazidMaleMycobacterium tuberculosisPyrazinamideRepublic of KoreaAntitubercular AgentsEthambutolIsoniazidPyrazinamideRifampinAdolescentChildMultidrug-ResistantPediatricTuberculosis

Identifiers

PMID28480653
PMCPMC5426251
OpenAlexW2610746166

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.