Evidence map›Paper›PMID 28480416›Full record

ArticleAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2017

Mmamosheledi Elsie Mothibe, Christinah Kahler-Venter, Elżbieta Osuch

Open access · diamondAbstract read
In one paragraph

Article in African journal of traditional, complementary, and alternative medicines : AJTCAM, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Cytotoxic and Antioxidant Effects of Antimalarial Herbal Mixtures.International journal of microbiology · 2020
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mmamosheledi Elsie MothibeSefako Makgatho Health Sciences University, Pretoria, Gauteng, South Africa.
Christinah Kahler-VenterSefako Makgatho Health Sciences University, Pretoria, Gauteng, South Africa.
Elżbieta OsuchSefako Makgatho Health Sciences University, Pretoria, Gauteng, South Africa.
Sefako Makgatho Health Sciences University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCommercial herbal medicines (CHMs) being marketed as immune boosters or tonics, have gained widespread popularity. The many herbal mixtures sold have not been tested for efficacy and safety, despite their modern packaging and presentations. It is imperative that these herbal mixtures be investigated for their effects on human neutrophils.

methodsThe selected herbal mixture (HM),

resultsThe HM had variable stimulatory and inhibitory effects on the luminescence activity of healthy isolated and non-isolated human neutrophils. The effects, ranging from weak to potent were either directly or inversely related to the concentration of the HM and were mediated through a direct protein kinase C activating mechanism and an indirect formyl peptide receptor-linked mechanism.

conclusionThe findings have shown the immunomodulatory potential of

Indexed as

PhytotherapyAdultDose-Response Relationship, DrugFemaleHealthy VolunteersHumansImmunologic FactorsLuminescenceMaleMedicine, African TraditionalNeutrophilsPlant PreparationsSouth AfricaImmunologic FactorsPlant Preparationsherbal medicinesinhibitionluminescenceneutrophilsstimulation

Identifiers

PMID28480416
PMCPMC5412238
OpenAlexW2592870546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.