Evidence map›Paper›PMID 28480382›Full record

Trial reportAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2017

THE EFFECT OF CAFFEINE SUPPLEMENTATION ON TRAINED INDIVIDUALS SUBJECTED TO MAXIMAL TREADMILL TEST.

Viviane Martins Mana Salicio, Carlos Alexandre Fett, Marcos Adriano Salicio, Camila Fernanda Costa Cunha Moraes Brandäo, Luiz Fabrizio Stoppiglia, Waléria Christiane Rezende Fett, And Clovis Botelho

Open access · diamondAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in African journal of traditional, complementary, and alternative medicines : AJTCAM, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Viviane Martins Mana SalicioPhysiotherapy Department of Várzea Grande University (UNIVAG). Education: Physiotherapy. Várzea Grande - MT, Brazil.
Carlos Alexandre FettLaboratory of the Research Center for Physical Fitness, Computers, Metabolism, Sport and Health. Federal University of Mato Grosso (NAFIMES-UFMT). Education: Physical Education. Cuiaba - MT, Brazil.
Marcos Adriano SalicioPhysiotherapy Department of Várzea Grande University (UNIVAG). Education: Physiotherapy. Várzea Grande - MT, Brazil.
Camila Fernanda Costa Cunha Moraes BrandäoLaboratory of the Research Center for Physical Fitness, Computers, Metabolism, Sport and Health. Federal University of Mato Grosso (NAFIMES-UFMT). Education: Physical Education. Cuiaba - MT, Brazil.
Luiz Fabrizio StoppigliaLaboratory of the Research Center for Physical Fitness, Computers, Metabolism, Sport and Health. Federal University of Mato Grosso (NAFIMES-UFMT). Education: Nutrition. Cuiaba - MT, Brazil.
Waléria Christiane Rezende FettLaboratory of the Research Center for Physical Fitness, Computers, Metabolism, Sport and Health. Federal University of Mato Grosso (NAFIMES-UFMT). Education: Physical Education. Cuiaba - MT, Brazil.
And Clovis BotelhoMedical School, Federal University of Mato Grosso (UFMT). Education: Medicine. Cuiaba - MT, Brazil.
Universidade Federal de Mato Grosso · BRCentro Universitário de Várzea Grande · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntense physical training increases oxidative stress and inflammation, resulting into muscle and cellular damage. The aim of this study was to analyze the effect of caffeine supplementation on trained young individuals subjected to two treadmill maximal tests. MATERIALS AND

methodsIt was a double-blind and crossover study comprising 24 active individuals within the age group 18-30 years. The comparisons were conducted: the effect of exercise (week 1 x 2) and caffeine intake (GC x GP) on thiobarbituric acid (TBARS), interleukin 6 (IL-6), interleukin 10 (IL-10) and superoxide dismutase (SOD) variables during pre-exercise time (30 min. after caffeine or placebo intake) and post-exercise (5 min after treadmill test).

resultsThe comparison between weeks 1 and 2 showed increase in the first week, in the following items: TBARS, IL-6 and IL-10 in the GC and GP groups. The comparison within the same week showed that GC individuals presented lower post-exercise TBARS values in the first and second weeks; IL- 6 presented higher post-exercise values in the GC group in both weeks. The paired analysis comparing pre- and post-exercise, with and without caffeine showed that IL-6 presented higher post-exercise values in the GC group.

conclusionCaffeine used by athletes can decrease oxidative stress. The increased IL-6 suggest that this ergogenic supplement may stimulate muscle hypertrophy, since IL-6 has myokine effect. However, the caffeine effect on IL-6 level and muscle hypertrophy increase should be better investigated in future studies.

Indexed as

AdultCaffeineCross-Over StudiesDietary SupplementsExercise TestFemaleHumansInterleukin-10Interleukin-6MaleOxidative StressResistance TrainingSuperoxide DismutaseYoung AdultCaffeineIL10 protein, humanIL6 protein, humanInterleukin-10Interleukin-6Superoxide DismutaseCaffeineExerciseInterleukinOxidative stress

Identifiers

PMID28480382
PMCPMC5411867
OpenAlexW2556919612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.