Evidence map›Paper›PMID 28480379›Full record

ArticleAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2016

CYTOTOXIC, α-CHYMOTRYPSIN AND UREASE INHIBITION ACTIVITIES OF THE PLANT

Muhammad Abuzar Ghaffari, Bashir Ahmed Chaudhary, Muhammad Uzair, Khuram Ashfaq

Open access · diamondAbstract read
In one paragraph

Article in African journal of traditional, complementary, and alternative medicines : AJTCAM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Muhammad Abuzar GhaffariFaculty of Pharmacy, Bahauddin Zakriya University, Multan, Pakistan.
Bashir Ahmed ChaudharyFaculty of Pharmacy, Bahauddin Zakriya University, Multan, Pakistan.
Muhammad UzairFaculty of Pharmacy, Bahauddin Zakriya University, Multan, Pakistan.
Khuram AshfaqFaculty of Pharmacy, Bahauddin Zakriya University, Multan, Pakistan.
Bahauddin Zakariya University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to investigate Cytotoxic, α-Chymotrypsin and Urease inhibition activities of the plant MATERIALS &

methodsDichloromethane and methanol extracts of the plant were evaluated for cytotoxic, α-Chymotrypsin and Urease inhibition by using

resultsThe methanol extract of the plant exhibited significant cytotoxic activity. Out of 30 brine shrimp larvae, 2 (6%), 26 (86%) and 28 (93%) larvae were survived at concentration of 1000μg/ml, 100μg/ml and 10μg/ml respectively with LD50; 215.837. Similarly 21 (70%), 25 (83%), 29 (96%) larvae were survived of dichloromethane plant extract with LD50; 6170.64. The methanol and dichloromethane extract exhibited 10.50±0.18% and 41.51±0.15% α-chymotrypsin enzyme inhibition respectively with IC

conclusionThe results clearly indicated that

Indexed as

AnimalsArtemiaChymotrypsinCytotoxinsHeliotropiumMethanolMethylene ChloridePlant ExtractsUreasealpha-chymotrypsinChymotrypsinCytotoxinsMethanolMethylene ChloridePlant ExtractsUreaseBrine Shrimp Lethality AssayCytotoxicityHeliotropium dasycarpum

Identifiers

PMID28480379
PMCPMC5412194
OpenAlexW2527689655

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.