Evidence map›Paper›PMID 28480354›Full record

ArticleAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2016

IMMUNO-MODULATORY PROPERTIES OF PREBIOTICS EXTRACTED FROM

Ezeonu Im, Asuquo Ae, Ukwah Bn, Ukoha Po

Open access · diamondAbstract read
In one paragraph

Article in African journal of traditional, complementary, and alternative medicines : AJTCAM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ezeonu ImDepartment of Microbiology, Faculty of Biological Sciences, University of Nigeria, Nsukka.
Asuquo AeDepartment of Microbiology, Faculty of Biological Sciences, University of Nigeria, Nsukka.
Ukwah BnDepartment of Medical Laboratory Sciences, Faculty of Health Sciences, Ebonyi State University, Abakaliki.
Ukoha PoDepartment of Pure and Industrial Chemistry, Faculty of Physical Sciences, University of Nigeria, Nsukka.
University of Nigeria · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsThe immuno-modulatory potential was evaluated by monitoring the effects of oral administration of the extract on immunological, haematological and lipid profiles of

resultsConsumption of the extract caused significant increases in CD4+-, white blood cell-, total lymphocyte- and high density lipid (HDL) counts; decreases in low density lipid (LDL) and triglycerides and no significant effect on haemoglobin (Hb) and packed cell volume (PCV) in the blood of test animals. The water-soluble fraction of the extract contained most of the phyto-constituents of the extract and Thin Layer Chromatographic analysis of the fraction revealed the presence of fructo-oligosaccharide and galacto-oligosaccharide prebiotics.

conclusionThe results from this study have shown that the aqueous leaf extract of

Indexed as

AnimalsCD4-Positive T-LymphocytesChromatography, Thin LayerGalactosidasesHematocritHemoglobinsImmunologic FactorsLeukocytesLipoproteins, HDLLipoproteins, LDLLymphocyte CountOligosaccharidesPlant ExtractsPlant LeavesPrebioticsRatsfructooligosaccharideGalactosidasesHemoglobinsImmunologic FactorsLipoproteins, HDLLipoproteins, LDLOligosaccharidesPlant ExtractsPrebioticsfructo-oligosaccharidegalacto-oligosaccharidehaematologyprebioticVernonia amygdalina

Identifiers

PMID28480354
PMCPMC5412181
OpenAlexW2523907484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.