Evidence map›Paper›PMID 28480292›Full record

ArticleOpen forum infectious diseases2017

Sex Disparity in Cord Blood FoxP3

Mary Prahl, Prasanna Jagannathan, Tara I McIntyre, Ann Auma, Samuel Wamala, Mayimuna Nalubega, Kenneth Musinguzi, Kate Naluwu, Esther Sikyoma, Rachel Budker and 6 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02282293 (Reducing the Burden of Malaria in HIV-Infected Pregnant Women and Their HIV-Exposed Children), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02282293 phase3completednot on this map

Reducing the Burden of Malaria in HIV-Infected Pregnant Women and Their HIV-Exposed Children (PROMOTE Birth Cohort 2)

TypeinterventionalSponsorUniversity of California, San FranciscoRan2014 to 2016Enrolled200ConditionsMalaria, Human Immunodeficiency VirusArmsMonthly dihydroartemisinin-piperaquine (DP) + daily trimethoprim/sulfamethoxazole (TS), Monthly placebo + daily trimethoprim/sulfamethoxazole (TS)
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. The immune response to malaria in utero.Immunological reviews · 2020
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Mary PrahlDepartments of Pediatrics and.
Prasanna JagannathanMedicine, University of California-San Francisco.
Tara I McIntyreMedicine, University of California-San Francisco.
Ann AumaInfectious Diseases Research Collaboration, Kampala, Uganda.
Samuel WamalaInfectious Diseases Research Collaboration, Kampala, Uganda.
Mayimuna NalubegaInfectious Diseases Research Collaboration, Kampala, Uganda.
Kenneth MusinguziInfectious Diseases Research Collaboration, Kampala, Uganda.
Kate NaluwuInfectious Diseases Research Collaboration, Kampala, Uganda.
Esther SikyomaInfectious Diseases Research Collaboration, Kampala, Uganda.
Rachel BudkerMedicine, University of California-San Francisco.
Pamela OdorizziMedicine, University of California-San Francisco.
Abel KakuruInfectious Diseases Research Collaboration, Kampala, Uganda.
Diane V HavlirMedicine, University of California-San Francisco.
Moses R KamyaSchool of Medicine, Makerere University of College of Health Sciences, College of Health Sciences, Kampala, Uganda.
Grant DorseyMedicine, University of California-San Francisco.
Margaret E FeeneyDepartments of Pediatrics and.
Infectious Diseases Research Collaboration · UGUniversity of California, San Francisco · USMakerere University · UG

Funding

The immunologic consequences of prenatal exposure to malariaP01HD059454 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAVLIR, DIANE V · 2008 to 2017
$22.6M
The role of γδ T cells in fetal and infant immune defense against malariaR01AI093615 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FEENEY, MARGARET E · 2011 to 2025
$9.1M
Training in HIV Translational ResearchT32AI060530 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Diane V Havlir · 2005 to 2026
$6.4M
Mentoring Translational Researchers for Careers in Pediatric Global HealthK24AI113002 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FEENEY, MARGARET E · 2014 to 2023
$1.9M
The Immunologic Impact of In Utero Malaria Exposure and Prenatal ChemopreventionK23AI127886 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PRAHL, MARY · 2017 to 2021
$1.0M
Immunologic Consequences of Highly Effective Antimalarial ChemopreventionK23AI100949 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAGANNATHAN, PRASANNA · 2012 to 2016
$657k
NIAID NIH HHS K24 AI113002NIAID NIH HHS R01 AI093615NIAID NIH HHS T32 AI060530NICHD NIH HHS P01 HD059454
6 · The paper itself

Abstract

Sex differences in the immune response and in infectious disease susceptibility have been well described, although the mechanisms underlying these differences remain incompletely understood. We evaluated the frequency of cord blood CD4 T cell subsets in a highly malaria-exposed birth cohort of mother-infant pairs in Uganda by sex. We found that frequencies of cord blood regulatory T cell ([T

Indexed as

immunitymalariasexT regulatory cellsvaccines.

Identifiers

PMID28480292
PMCPMC5414097
OpenAlexW2588244802

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.