Evidence map›Paper›PMID 28480290›Full record

ArticleOpen forum infectious diseases2017

Group B Streptococci Colonization in Pregnant Guatemalan Women: Prevalence, Risk Factors, and Vaginal Microbiome.

Anne-Marie Rick, Angie Aguilar, Rosita Cortes, Remei Gordillo, Mario Melgar, Gabriela Samayoa-Reyes, Daniel N Frank, Edwin J Asturias

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Influence of group BWorld journal of clinical cases · 2022
    Article
  11. Updates on Group BMicroorganisms · 2022
    Review
  12. Review
  13. Protective Effect ofPathogens (Basel, Switzerland) · 2022
    Article
  14. Vertical Transmission, Risk Factors, and Antimicrobial Resistance Patterns of Group BThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. [Relationship of group BZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2020
    Article
  19. Article
  20. Group BMicrobiology spectrum · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Anne-Marie RickDepartment of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora.
Angie AguilarFacultad de Medicina, Universidad Francisco Marroquín, Guatemala City.
Rosita CortesDepartment of Pediatrics and Microbiology, Hospital Roosevelt, Guatemala City.
Remei GordilloDepartment of Pediatrics and Microbiology, Hospital Roosevelt, Guatemala City.
Mario MelgarDepartment of Pediatrics and Microbiology, Hospital Roosevelt, Guatemala City.
Gabriela Samayoa-ReyesDepartment of Microbiology and Immunology, University of Colorado, Aurora.
Daniel N FrankDivision of Infectious Diseases, School of Medicine, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora.
Edwin J AsturiasDepartment of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora.
Roosevelt Hospital · GTUniversity of Colorado Anschutz Medical Campus · USChildren's Hospital Colorado · USUniversidad Francisco Marroquín · GTUniversity of Colorado Denver · US

Funding

Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
NCATS NIH HHS UL1 TR001082
6 · The paper itself

Abstract

backgroundInfection causes 1 of every 5 neonatal deaths globally. Group B

methodsA cross-sectional study in 2015 at a public hospital in Guatemala City enrolled women ≥35 weeks' gestation. Vaginal and rectal swabs were processed using Lim broth and GBS CHROMagar then agglutination testing. Risk factors were assessed using multivariate analysis. Vaginal microbiota were profiled by 16S ribosomal ribonucleic acid sequencing in a subset of 94 women.

resultsOf 896 pregnant women, 155 (17.3%; 95% confidence interval [CI], 14.9-19.9) were GBS colonized. Colonization was associated with history of previous infant with poor outcome (odds ratio [OR], 1.94; 95% CI, 1.15-3.27) and increasing maternal age (OR, 1.05; 95% CI, 1.02-1.09). Multiparity was protective (OR, .39; 95% CI, .21-.72). Four (6%) GBS-exposed infants had early-onset neonatal sepsis. Vaginal microbiome composition was associated with previous antibiotic exposure (

conclusionsGroup B

Indexed as

colonizationGBSpregnancyStreptococcus agalactiaevaginal microbiome.

Identifiers

PMID28480290
PMCPMC5414013
OpenAlexW2586260025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.