Evidence map›Paper›PMID 28480254›Full record

ArticleOpen forum infectious diseases2017

Disseminated Cryptococcosis With Brain Involvement in Patients With Chronic Lymphoid Malignancies on Ibrutinib.

Julia A Messina, Eileen K Maziarz, Andrej Spec, Dimitrios P Kontoyiannis, John R Perfect

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Journal of fungi (Basel, Switzerland) · 2021
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Promises and pitfalls of targeted agents in chronic lymphocytic leukemia.Cancer drug resistance (Alhambra, Calif.) · 2020
    Review
  13. Review
  14. Article
  15. Antibody immunity and natural resistance to cryptococcosis.Current tropical medicine reports · 2019
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Serious Infections in Patients Receiving Ibrutinib for Treatment of Lymphoid Cancer.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Julia A MessinaDepartment of Medicine, Duke University, Durham, North Carolina.
Eileen K MaziarzDepartment of Medicine, Duke University, Durham, North Carolina.
Andrej SpecDivision of Infectious Disease, Washington University, St. Louis, Missouri.
Dimitrios P KontoyiannisUniversity of Texas MD Anderson Cancer Center, Houston.
John R PerfectDepartment of Medicine, Duke University, Durham, North Carolina.
Duke University · USThe University of Texas MD Anderson Cancer Center · USWashington University in St. Louis · US

Funding

Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTGT32AI100851 · NIAID · DUKE UNIVERSITY · PI ALEXANDER, BARBARA D · 2013 to 2022
$1.8M
NIAID NIH HHS T32 AI100851
6 · The paper itself

Abstract

We report 2 cases of disseminated cryptococcosis with central nervous system involvement in patients with chronic lymphoid malignancies occurring within 1 month of starting on ibrutinib. Characteristically, in both cases, no inflammation was seen in the cerebrospinal fluid. Central nervous system mycoses should be considered as a potential complication of ibrutinib.

Indexed as

CARD9central nervous system mycosis; chronic lymphoid malignanciescryptococcosisibrutinib.

Identifiers

PMID28480254
PMCPMC5413986
OpenAlexW2562641802

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.