ArticleOpen forum infectious diseases2017
High Incidence of Invasive Group A Streptococcal Infections in Remote Indigenous Communities in Northwestern Ontario, Canada.
Article in Open forum infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Clinical Presentation and Management of Patients Referred for Transthoracic Echocardiography in Canada's Arctic Region.CJC open · 2026Article
- Burden of invasive group a streptococcus infection in Australia: a systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Review
- Refractory Cervical Necrotizing Fasciitis Successfully Controlled by Submandibular Gland Excision: A Case Report.Clinical case reports · 2026Article
- Why, Immunologically, Housing-Related Fungi and Endotoxins (and Other Chronic Pro-Inflammatory Stressors) Risk Latent Tuberculosis Reactivation, Severe Asthma, and Translocating and Invasive Infections in Indigenous Communities in Canada.American journal of human biology : the official journal of the Human Biology Council · 2026Review
- A Rare Case of Ischial Tubercle Pressure Sore with Secondary Periperineal Necrotizing FasciitisEndocrine, metabolic & immune disorders drug targets · 2026Article
- Article
- Group A Streptococcus among American Indian Persons, White Mountain Apache Tribal Lands, United States, 2016-2019Emerging infectious diseases · 2025Article
- A Study on the Accuracy of Point-of-Care Ultrasound in the Diagnosis and Management of Necrotizing Fasciitis.Cureus · 2025Article
- Etiology of community-acquired bacterial meningitis in children at a tertiary-care centre in Montreal, Canada.Paediatrics & child health · 2025Article
- The Role of Physical Examination and Clinical Scores in Distinguishing Streptococcal Colonization from Pharyngitis in Pediatric Patients: Insights from a Common Clinical Scenario.Microorganisms · 2025Article
- Choosing Wisely: Effectiveness and Safety of Antibiotic Prophylaxis in Close Contacts of Invasive Group A Streptococci Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- Predicting mortality in necrotizing fasciitis: Retrospective evaluation of 69 cases.Northern clinics of Istanbul · 2025Article
- Burden of antimicrobial prescribing in primary care attributable to sore throat: a retrospective cohort study of patient record data.BMC primary care · 2024Article
- Disruption of IL-17-mediated immunosurveillance in the respiratory mucosa results in invasiveFrontiers in immunology · 2024Article
- Emergence of Erythromycin-Resistant Invasive Group A Streptococcus, West Virginia, USA, 2020-2021.Emerging infectious diseases · 2023Article
- Outcomes in necrotizing soft tissue infections are worse in rural versus urban Montana: a 10-year single center retrospective review.International journal of burns and trauma · 2023Article
- Group A Streptococcus Infections: Their Mechanisms, Epidemiology, and Current Scope of Vaccines.Cureus · 2022Review
- Retroperitoneal necrotizing soft tissue infections: A case report and literature review.Clinical case reports · 2022Article
- Review
- Dimensions of poverty as risk factors for antimicrobial resistant organisms in Canada: a structured narrative review.Antimicrobial resistance and infection control · 2022Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWorldwide, indigenous populations appear to be at increased risk for invasive group A streptococcal (iGAS) infections. Although there is empirical evidence that the burden of iGAS disease is significant among remote First Nations communities in Northwestern Ontario, Canada, the epidemiology of iGAS infections in the area remains poorly characterized.
methodsIndividuals that met case definition for iGAS disease and whose laboratory specimens were processed by Meno Ya Win Health Centre in Sioux Lookout, Canada or who were reported to Thunder Bay District Health Unit, Canada were identified for the period 2009 to 2014. Case demographics, clinical severity, comorbidities, and risk factors were collected through chart review. Strain typing and antibiotic susceptibility were determined when possible. Basic descriptive statistics were calculated.
resultsSixty-five cases of iGAS disease were identified, for an annualized incidence of 56.2 per 100 000. Primary bacteremia was present in 26.2% of cases, and cellulitis was identified in 55.4% of cases. The most common comorbidities identified were diabetes (38.5%) and skin conditions (38.5%). Prevalent risk factors included alcohol dependence (25%). Fourteen different
conclusionsRural and remote First Nations communities in Northwestern Ontario experience iGAS infections at a rate 10 times the provincial and national average. Compared with other North American series, a lower proportion of isolates causing infection were of
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