ArticleACS sustainable chemistry & engineering2016
Catalytic Upgrading in Bacteria-Compatible Conditions via a Biocompatible Aldol Condensation.
Article in ACS sustainable chemistry & engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Biocompatible α-Methylenation of Metabolic Butyraldehyde in Living Bacteria.Angewandte Chemie (International ed. in English) · 2023Article
- Tyramine Derivatives Catalyze the Aldol Dimerization of Butyraldehyde in the Presence of Escherichia coli.Chembiochem : a European journal of chemical biology · 2022Article
- Article
- Interfacing non-enzymatic catalysis with living microorganisms.RSC chemical biology · 2021Review
- A Screening Platform to Identify and Tailor Biocompatible Small-Molecule Catalysts.Chemistry (Weinheim an der Bergstrasse, Germany) · 2019Article
- Caged Proline in Photoinitiated Organocatalysis.The Journal of organic chemistry · 2019Article
- Biocatalytic activity of Monascus mycelia depending on physiology and high sensitivity to product concentration.AMB Express · 2017Article
- Light-Driven Catalytic Upgrading of Butanol in a Biohybrid Photoelectrochemical System.ACS sustainable chemistry & engineering · 2017Article
- Multicatalytic, Light-Driven Upgrading of Butanol to 2-Ethylhexenal and Hydrogen under Mild Aqueous Conditions.ACS catalysis · 2017Article
- Conversion of Ethanol to 2-Ethylhexenal at Ambient Conditions Using Tandem, Biphasic Catalysis.ACS sustainable chemistry & engineering · 2017Article
- Designer Micelles Accelerate Flux Through Engineered Metabolism in E. coli and Support Biocompatible Chemistry.Angewandte Chemie (International ed. in English) · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Integrating non-enzymatic chemistry with living systems has the potential to greatly expand the types and yields of chemicals that can be sourced from renewable feedstocks. The in situ conversion of microbial metabolites to higher order products will ensure their continuous generation starting from a given cellular reaction mixture. We present here a systematic study of different organocatalysts that enable aldol condensation in biological media under physiological conditions of neutral pH, moderate temperature, and ambient pressure. The relative toxicities of each catalyst were tested against bacteria, and the catalysts were found to provide good yields of homoaldol products in bacterial cultures containing aldehydes. Lastly, we demonstrate that a biocompatible oil can be used to selectively extract the upgraded products, which enabes facile isolation and decreases the product toxicity to microbes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.