Evidence map›Paper›PMID 28480138›Full record

ArticlePeerJ2017

vConTACT: an iVirus tool to classify double-stranded DNA viruses that infect

Benjamin Bolduc, Ho Bin Jang, Guilhem Doulcier, Zhi-Qiang You, Simon Roux, Matthew B Sullivan

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 189 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
189citing papers in PubMed, 2 pooled it
20.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

189 citing papers in PubMed, 2 syntheses or guidelines pooled it, 301 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  14. Hawaiian Geothermal Fumaroles Contain Diverse and Novel Viruses.bioRxiv : the preprint server for biology · 2026
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  18. Discovery and characterization of a novelPHAGE (New Rochelle, N.Y.) · 2026
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129 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Benjamin Bolduc *Department of Microbiology, Ohio State University, Columbus, OH, United States.
Ho Bin Jang *Department of Microbiology, Ohio State University, Columbus, OH, United States.
Guilhem DoulcierInstitut de Biologie de l'ENS (IBENS), École normale supérieure, PSL Research University, Paris, France.
Zhi-Qiang YouDepartment of Chemistry and Biochemistry, Ohio State University, Columbus, OH, United States.
Simon RouxDepartment of Microbiology, Ohio State University, Columbus, OH, United States.
Matthew B SullivanDepartment of Microbiology, Ohio State University, Columbus, OH, United States.
The Ohio State University · USInstitut de Biologie de l'École Normale Supérieure · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Taxonomic classification of archaeal and bacterial viruses is challenging, yet also fundamental for developing a predictive understanding of microbial ecosystems. Recent identification of hundreds of thousands of new viral genomes and genome fragments, whose hosts remain unknown, requires a paradigm shift away from traditional classification approaches and towards the use of genomes for taxonomy. Here we revisited the use of genomes and their protein content as a means for developing a viral taxonomy for bacterial and archaeal viruses. A network-based analytic was evaluated and benchmarked against authority-accepted taxonomic assignments and found to be largely concordant. Exceptions were manually examined and found to represent areas of viral genome 'sequence space' that are under-sampled or prone to excessive genetic exchange. While both cases are poorly resolved by genome-based taxonomic approaches, the former will improve as viral sequence space is better sampled and the latter are uncommon. Finally, given the largely robust taxonomic capabilities of this approach, we sought to enable researchers to easily and systematically classify new viruses. Thus, we established a tool, vConTACT, as an app at iVirus, where it operates as a fast, highly scalable, user-friendly app within the free and powerful CyVerse cyberinfrastructure.

Indexed as

Archaeal virusesBacteriophageTaxonomyVirus

Identifiers

PMID28480138
PMCPMC5419219
OpenAlexW2610784236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.