ReviewJournal of clinical and translational science2017
Mapping the evolving definitions of translational research.
Review in Journal of clinical and translational science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
92 citing papers in PubMed, 3 syntheses or guidelines pooled it, 188 citations in OpenAlex.
- From Bench to Bedside: Evolving Definitions of Translational Research.Saudi medical journal · 2026Pooled it
- Exploring Translational Medical Research Progress in G20 Countries:Saudi medical journal · 2026Pooled it
- Pooled it
- Supporting community translation of lung cancer screening: A web-based decision aid to support informed decision making.Translational behavioral medicine · 2025Trial
- A lifecycle governance and learning health system framework for trustworthy, generalizable, and sustainable human-ai partnership in clinical practice: Lessons from the asthma-guidance and prediction system (A-GPS).Journal of the National Medical Association · 2026Review
- The Design and Conduct of Cohort Studies of Peoples With CKD - International Perspectives From iNET-CKD.Kidney international reports · 2026Article
- Stabilizing and strengthening the US physician-scientist faculty workforce in academic medicine: a proposed institutional framework.JCI insight · 2026Article
- Enhancing the Efficacy of Exposure Therapy: Translation of Pharmacological Augmentation of Fear Extinction.Annual review of clinical psychology · 2026Review
- Driving innovation in cancer symptom science through translational research: bridging science and practice.Current opinion in supportive and palliative care · 2026Review
- When Did the Term "Translational Research" Emerge-and Why?Journal of Korean medical science · 2026Article
- Dissemination and implementation science for global ophthalmology: closing the last-mile translational gap.Frontiers in public health · 2026Review
- Designing for impact: Introducing translational design studies.Journal of clinical and translational science · 2026Article
- The Forge AHEAD Center Pilot Plus program: An integrated framework combining pilot funding, training, and community-engaged translational science.Journal of clinical and translational science · 2026Article
- Embracing complexity: An opportunity for developmental evaluation.Journal of clinical and translational science · 2026Article
- Translational medicine: An effective approach to improve healthcare by research and innovation in developing countries.Medicine · 2025Review
- Could master protocols be adapted for effectiveness-implementation hybrid studies?BMC medical research methodology · 2025Article
- Imparting the core competencies of a scientific scholar through a week-long focused course: a pre-post study in Swiss undergraduate medical students.BMC medical education · 2025Article
- State-of-the-Art Organ-on-Chip Models and Designs for Medical Applications: A Systematic Review.Biomimetics (Basel, Switzerland) · 2025Review
- Defusing political animosity in the United States with a cooperative online quiz game.Nature human behaviour · 2025Article
- Engagement, Dissemination, and Implementation: A Review of the Correctional Health Studies funded by the National Institute of Health's HEAL Initiatives.Victims & offenders · 2025Article
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveSystematic review and analysis of definitions of translational research. MATERIALS AND
methodsThe final corpus was comprised of 33 papers, each read by at least 2 reviewers. Definitions were mapped to a common set of research processes for presentation and analysis. Influence of papers and definitions was further evaluated using citation analysis and agglomerative clustering.
resultsAll definitions were mapped to common research processes, revealing most common labels for each process. Agglomerative clustering revealed 3 broad families of definitions. Citation analysis showed that the originating paper of each family has been cited ~10 times more than any other member. DISCUSSION: Although there is little agreement between definitions, we were able to identify an emerging consensus 5-phase (T0-T4) definition for translational research. T1 involves processes that bring ideas from basic research through early testing in humans. T2 involves the establishment of effectiveness in humans and clinical guidelines. T3 primarily focuses on implementation and dissemination research while T4 focuses on outcomes and effectiveness in populations. T0 involves research such as genome-wide association studies which wrap back around to basic research.
conclusionWe used systematic review and analysis to identify emerging consensus between definitions of translational research phases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.