Evidence map›Paper›PMID 28479925›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2017

Inhibition of Cardiac Hypertrophy Effects in D-Galactose-Induced Senescent Hearts by

Yung-Ming Chang, Hen-Hong Chang, Hung-Jen Lin, Chin-Chuan Tsai, Chuan-Te Tsai, Hsin-Nung Chang, Shu-Luan Lin, Vijaya PadmaViswanadha, Ray-Jade Chen, Chih-Yang Huang

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

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  12. Mangiferin ameliorates cardiac fibrosis in D-galactose-induced aging rats by inhibiting TGF-β/p38/MK2 signaling pathway.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Yung-Ming ChangThe School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung 840, Taiwan.
Hen-Hong ChangResearch Center for Chinese Medicine & Acupuncture, China Medical University, Taichung 404, Taiwan.ORCID 0000-0002-7840-1504
Hung-Jen LinDepartment of Chinese Medicine, China Medical University Hospital, Taichung 404, Taiwan.
Chin-Chuan TsaiThe School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung 840, Taiwan.
Chuan-Te Tsai1PT Biotechnology Co., Ltd., Taichung 433, Taiwan.
Hsin-Nung ChangGraduate Institute of Basic Medical Science, China Medical University, Taichung 404, Taiwan.
Shu-Luan Lin1PT Lukang Chinese Medicine Clinics, Changhua 505, Taiwan.
Vijaya PadmaViswanadhaDepartment of Biotechnology, Bharathiar University, Coimbatore 641046, India.
Ray-Jade ChenDepartment of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Chih-Yang HuangGraduate Institute of Basic Medical Science, China Medical University, Taichung 404, Taiwan.ORCID 0000-0003-2347-0411
E-Da Hospital · TWZhejiang Chinese Medical University · CNBharathiar University · INChina Medical University · TWTaipei Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging is a complex physiological phenomenon accelerated by ROS accumulation, with multisystem decline and increasing vulnerability to degenerative diseases and death. Cardiac hypertrophy is a key pathophysiological component that accompanies the aging process. Alpinate Oxyphyllae Fructus (

Identifiers

PMID28479925
PMCPMC5396449
OpenAlexW2605220841

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.