ArticleAfrican health sciences2016
Socio-demographic correlates of treatment response among patients with schizophrenia in a tertiary hospital in South-East Nigeria.
Article in African health sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.
- Predictors of long-term outcome of patients with schizophrenia in Africa: systematic review and meta-analysis.BMC public health · 2025Pooled it
- Antipsychotic Medication in Sub-Saharan Africa: A Systematic Literature Review.Journal of clinical psychopharmacologyPooled it
- Article
- Child, reproductive, mental health; infections and NCDs in the African environment.African health sciences · 2016Article
- Prevalence of Working Memory Impairment in Drug Naive Schizophrenic Patients in a Tertiary Care Hospital.JNMA; journal of the Nepal Medical AssociationArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMany patients with schizophrenia respond poorly to antipsychotic medication. Few studies have systematically examined the relationship of social and demographic characteristics of these patients to treatment response in our environment.
objectiveTo identify the social and demographic variables associated with treatment response in patients with schizophrenia.
methodA total of 172 participants with a diagnosis of schizophrenia receiving antipsychotics took part in the study. Participants were consecutively recruited involving patients presenting for the first time, or relapsed patients who had stopped antipsychotics in the previous six months. Both in-patients and out-patients who met the inclusion criteria were studied. Socio-demographic interview schedule and the Positive and Negative Syndrome Scale (PANSS) were administered at the initial encounter and between 4 and 6 weeks, subsequently.
resultsDefining good treatment response as ≥ 20% reduction in PANSS score, 68% had a good response while 32% had poor response. Good response to treatment was associated with late age of onset of illness, satisfactory family relationship, acquisition of skilled occupation and being married. However, there was no association between treatment response and gender.
conclusionKnowledge about these variables in relation to treatment response would improve mental health services as regards articulation of prognosis and psycho education.
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