ArticleProceedings of the ... American Control Conference. American Control Conference2014
MPC Design for Rapid Pump-Attenuation and Expedited Hyperglycemia Response to Treat T1DM with an Artificial Pancreas.
Article in Proceedings of the ... American Control Conference. American Control Conference, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Outpatient Closed-Loop Control with Unannounced Moderate Exercise in Adolescents Using Zone Model Predictive Control.Diabetes technology & therapeutics · 2017Trial
- Randomized Crossover Comparison of Personalized MPC and PID Control Algorithms for the Artificial Pancreas.Diabetes care · 2016Trial
- Adjustment of Open-Loop Settings to Improve Closed-Loop Results in Type 1 Diabetes: A Multicenter Randomized Trial.The Journal of clinical endocrinology and metabolism · 2015Trial
- Velocity-weighting & velocity-penalty MPC of an artificial pancreas: Improved safety & performance.Automatica : the journal of IFAC, the International Federation of Automatic Control · 2018Article
- An Enhanced Model Predictive Control for the Artificial Pancreas Using a Confidence Index Based on Residual Analysis of Past Predictions.Journal of diabetes science and technology · 2017Article
- Periodic zone-MPC with asymmetric costs for outpatient-ready safety of an artificial pancreas to treat type 1 diabetesAutomatica : the journal of IFAC, the International Federation of Automatic Control · 2016Article
- Switched LPV Glucose Control in Type 1 Diabetes.IEEE transactions on bio-medical engineering · 2016Article
- Reducing Glucose Variability Due to Meals and Postprandial Exercise in T1DM Using Switched LPV Control: In Silico Studies.Journal of diabetes science and technology · 2016Article
- Velocity-weighting to prevent controller-induced hypoglycemia in MPC of an artificial pancreas to treat T1DM.Proceedings of the ... American Control Conference. American Control Conference · 2015Article
- Tackling problem nonlinearities & delays via asymmetric, state-dependent objective costs in MPC of an artificial pancreas.IFAC-PapersOnLine · 2015Article
- Design of an Artificial Pancreas using Zone Model Predictive Control with a Moving Horizon State Estimator.Proceedings of the ... IEEE Conference on Decision & Control. IEEE Conference on Decision & Control · 2014Article
- Moving-horizon-like state estimation via continuous glucose monitor feedback in MPC of an artificial pancreas for type 1 diabetes.Proceedings of the ... IEEE Conference on Decision & Control. IEEE Conference on Decision & Control · 2014Article
- State Estimation with Sensor Recalibrations and Asynchronous Measurements for MPC of an Artificial Pancreas to Treat T1DM.Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The design of a Model Predictive Control (MPC) strategy for the closed-loop operation of an Artificial Pancreas (AP) for treating Type 1 Diabetes Mellitus (T1DM) is considered in this paper. The contribution of this paper is to propose two changes to the usual structure of the MPC problems typically considered for control of an AP. The first proposed change is to replace the symmetric, quadratic input cost function with an asymmetric, quadratic function, allowing negative control inputs to be penalized less than positive ones. This facilitates rapid pump-suspensions in response to predicted hypoglycemia, while simultaneously permitting the design of a conservative response to hyperglycemia. The second proposed change is to penalize the velocity of the predicted glucose level, where this velocity penalty is based on a cost function that is again asymmetric, but additionally state-dependent. This facilitates the accelerated response to acute, persistent hyperglycemic events, e.g., as induced by unannounced meals. The novel functionality is demonstrated by numerical examples, and the efficacy of the proposed MPC strategy verified using the University of Padova/Virginia metabolic simulator.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.