Evidence map›Paper›PMID 28479625›Full record

ArticleBulletin of the World Health Organization2017

Lessons learnt from 12 oral cholera vaccine campaigns in resource-poor settings.

Amber Hsiao, Sachin N Desai, Vittal Mogasale, Jean-Louis Excler, Laura Digilio

Open access · diamondAbstract read
In one paragraph

Article in Bulletin of the World Health Organization, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
  2. Recent epidemiological and management approaches for cholera in India.Proceedings (Baylor University. Medical Center) · 2026
    Review
  3. Cost of Cholera for Households and Health Facilities, Somalia.Journal of epidemiology and global health · 2024
    Article
  4. Diagnosis, Management, and Future Control of Cholera.Clinical microbiology reviews · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amber HsiaoDevelopment and Delivery Unit, International Vaccine Institute, SNU Research Park, 1 Gwanak-ro, Seoul, 08826, Republic of Korea.
Sachin N DesaiDevelopment and Delivery Unit, International Vaccine Institute, SNU Research Park, 1 Gwanak-ro, Seoul, 08826, Republic of Korea.
Vittal MogasaleDepartment of Policy and Economic Research, International Vaccine Institute, Seoul, Republic of Korea.
Jean-Louis ExclerDepartment of Clinical Development and Regulatory, International Vaccine Institute, Seoul, Republic of Korea.
Laura DigilioDevelopment and Delivery Unit, International Vaccine Institute, SNU Research Park, 1 Gwanak-ro, Seoul, 08826, Republic of Korea.
International Vaccine Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Improving water and sanitation is the preferred choice for cholera control in the long-term. Nevertheless, vaccination is an available tool that has been shown to be a cost-effective option for cholera prevention in endemic countries or during outbreaks. In 2011 the first low-cost oral cholera vaccine for international use was given prequalification by the World Health Organization (WHO). To increase and prioritize use of the vaccine, WHO created a global stockpile in 2013 from which countries may request oral cholera vaccine for reactive campaigns. WHO has issued specific guidelines for applying for the vaccine, which was previously in short supply (despite prequalification for a second oral vaccine in 2015). The addition of a third WHO-prequalified oral cholera vaccine in 2016 is expected to increase the global stockpile considerably and alleviate supply issues. However, prioritization and best use of the vaccine (e.g. how, when and where to use) will remain challenges. We describe 12 past oral cholera vaccine campaigns, conducted in settings with varying burdens of cholera. These case studies illustrate three key challenges faced in the use of the oral cholera vaccines: regulatory hurdles, cold chain logistics and vaccine coverage and uptake. To pave the way for the introduction of current and future oral cholera vaccines, we discuss operational challenges and make recommendations for future research with respect to each of these challenges.

Indexed as

Developing CountriesAdministration, OralBiomedical ResearchCholeraCholera VaccinesCost-Benefit AnalysisDisease OutbreaksDrug StorageHumansWorld Health OrganizationCholera Vaccines

Identifiers

PMID28479625
PMCPMC5407249
OpenAlexW2603439230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.