Evidence map›Paper›PMID 28479164›Full record

ReviewBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2017

Recommendations for Screening and Management of Late Effects in Patients with Severe Combined Immunodeficiency after Allogenic Hematopoietic Cell Transplantation: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric HCT.

Jennifer Heimall, Rebecca H Buckley, Jennifer Puck, Thomas A Fleisher, Andrew R Gennery, Elie Haddad, Benedicte Neven, Mary Slatter, Skinner Roderick, K Scott Baker and 6 more

Open access · greenAbstract readReviewConsensus Statement
In one paragraph

Review in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 3 countries.

Jennifer HeimallDivision of Allergy and Immunology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: heimallj@email.chop.edu.
Rebecca H BuckleyDepartments of Pediatrics and Immunology, Duke University Medical Center, Durham, North Carolina.
Jennifer PuckDepartment of Pediatrics, Allergy, Immunology, and Blood and Marrow Transplant Division, University of California San Francisco, San Francisco California, California.
Thomas A FleisherDepartment of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland.
Andrew R GenneryDepartment of Paediatric Immunology, Newcastle upon Tyne, United Kingdom Institute of Cellular Medicine, Newcastle upon Tyne University, Newcastle upon Tyne, United Kingdom.
Elie HaddadDepartment of Pediatrics, Department of Microbiology, Infection and Immunology, University of Montreal, CHU Sainte-Justine, Montreal, Quebec, Canada.
Benedicte NevenDepartment of Immunology, Bone Marrow Transplantation, Hospital Necker Enfants Malades, Paris, France.
Mary SlatterDepartment of Paediatric Immunology, Newcastle upon Tyne, United Kingdom Institute of Cellular Medicine, Newcastle upon Tyne University, Newcastle upon Tyne, United Kingdom.
Skinner RoderickGreat North Children's Hospital and Northern Institute of Cancer Research, Newcastle upon Tyne, United Kingdom.
K Scott BakerClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Andrew C DietzChildren's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, California.
Christine DuncanDana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
Linda M GriffithDivision of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland.
Luigi NotarangeloLaboratory of Host Defenses, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland.
Michael A PulsipherDana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
Morton J CowanDepartment of Pediatrics, Allergy, Immunology, and Blood and Marrow Transplant Division, University of California San Francisco, San Francisco California, California.
National Institutes of Health · USDana-Farber/Boston Children's Cancer and Blood Disorders Center · USNewcastle University · GBUniversity of California, San Francisco · USCentre Hospitalier Universitaire Sainte-Justine · CAChildren's Hospital of Los Angeles · USChildren's Hospital of Philadelphia · USDuke Medical Center · USFred Hutch Cancer Center · USInstitute of Cancer Research · GB

Funding

Rare Diseases Data Management and Coordinating CenterU01TR001263 · NCATS · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2014 to 2018
$28.1M
Training of Clinical Investigators in Primary Immune DeficienciesU54AI082973 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PUCK, JENNIFER M. · 2009 to 2023
$23.3M
Data Management and Coordinating Center (DMCC)U54NS064808 · NINDS · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2009 to 2013
$16.5M
Characterization of the cellular and molecular bases of inborn errors of immunityZIAAI001222 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NOTARANGELO, LUIGI · 2017 to 2025
$15.2M
Pediatric Blood and Marrow Transplant ConsortiumU01HL069254 · NHLBI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI PULSIPHER, MICHAEL A · 2001 to 2010
$2.0M
Primary Immune Deficiency Treatment Consortium Annual Scientific MeetingR13AI094943 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PUCK, JENNIFER M. · 2011 to 2025
$239k
Late Effects after Pediatric HSCT: State of the Science, Future DirectionsR13CA159788 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI BAKER, KEVIN S, PULSIPHER, MICHAEL A · 2011 to 2011
$13k
NCATS NIH HHS U01 TR001263NCI NIH HHS R13 CA159788NHLBI NIH HHS U01 HL069254NIAID NIH HHS R13 AI094943NIAID NIH HHS U54 AI082973NINDS NIH HHS U54 NS064808
6 · The paper itself

Abstract

Severe combined immunodeficiency (SCID) is effectively treated with hematopoietic cell transplantation (HCT), with overall survival approaching 90% in contemporary reports. However, survivors are at risk for developing late complications because of the variable durability of high-quality immune function, underlying genotype of SCID, comorbidities due to infections in the pretransplantation and post-transplantation periods, and use of conditioning before transplantation. An international group of transplantation experts was convened in 2016 to review the current knowledge of late effects seen in SCID patients after HCT and to develop recommendations for screening and monitoring for late effects. This report provides recommendations for screening and management of pediatric and adult SCID patients treated with HCT.

Indexed as

Hematopoietic Stem Cell TransplantationAdolescentAdultAllograftsChildChild, PreschoolConsensusFemaleHumansInfantInfant, NewbornMalePractice Guidelines as TopicSevere Combined ImmunodeficiencyBone marrow transplantationLong-term follow-up guidelinesSevere combined immune deficiency

Identifiers

PMID28479164
PMCPMC6015789
OpenAlexW2610914955

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.