ArticleEuropean journal of oncology nursing : the official journal of European Oncology Nursing Society2017
Differences in symptom clusters identified using symptom occurrence rates versus severity ratings in patients with breast cancer undergoing chemotherapy.
Article in European journal of oncology nursing : the official journal of European Oncology Nursing Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Internet-Based Interventions in Quality of Life Assessments Among Women Living With Breast Cancer: A Systematic and Meta-Analytic Approach.Cancer reports (Hoboken, N.J.) · 2025Pooled it
- Experiences of Patients With Cancer Using Electronic Symptom Management Systems: Qualitative Systematic Review and Meta-Synthesis.Journal of medical Internet research · 2024Pooled it
- Symptom clusters in patients receiving chemotherapy: A systematic review.BMJ supportive & palliative care · 2022Pooled it
- Symptom clusters experienced by breast cancer patients at various treatment stages: A systematic review.Cancer medicine · 2021Pooled it
- Reduced symptom burden with the support of an interactive app during neoadjuvant chemotherapy for breast cancer - A randomized controlled trial.Breast (Edinburgh, Scotland) · 2020Trial
- Music, heart rate variability, and symptom clusters: a comparative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Trial
- Anxiety in breast cancer research (1982-2024): a bibliometric analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Using confirmatory factor analysis to identify symptom clusters in individuals with acquired disabilities.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Symptom Clusters in Brazilian Women With Stage I and Stage III Nonmetastatic Breast Cancer: A Cross-Sectional Study.The breast journal · 2026Article
- State of the "Art" in Precision Health Symptom Science Research.Seminars in oncology nursing · 2025Review
- The need for comprehensive sleep disturbances assessment and management in breast cancer care.Scientific reports · 2025Observational
- Differences in symptom clusters based on multidimensional symptom experience and symptom burden in stroke patients.Scientific reports · 2025Article
- Symptom clusters and networks analysis in acute-phase stroke patients: a cross-sectional study.Scientific reports · 2025Article
- Preliminary Analysis of Gut Microbiome and Gastrointestinal Symptom Burden in Breast Cancer Patients Receiving Chemotherapy Compared to Healthy Controls.Biological research for nursing · 2024Article
- Stability and consistency of symptom clusters in younger versus older patients receiving chemotherapy.BMC geriatrics · 2024Article
- Symptom clusters in oncology outpatients: stability and consistency across a cycle of chemotherapy.BMJ supportive & palliative care · 2024Article
- Identifying symptom cluster in cancer patients undergoing chemotherapy-in Vietnam: A cross-sectional study.PloS one · 2024Article
- Network analysis to identify symptoms clusters and temporal interconnections in oncology patients.Scientific reports · 2022Article
- Symptom clusters in outpatients with cancer using different dimensions of the symptom experience.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- HIV Symptom Clusters are Similar Using the Dimensions of Symptom Occurrence and Distress.Journal of pain and symptom management · 2022Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
purposeOne of the unanswered questions in symptom clusters research is whether the number and types of symptom clusters vary based on the dimension of the symptom experience used to create the clusters. Given that patients with breast cancer receiving chemotherapy (CTX), report between 10 and 32 concurrent symptoms and studies of symptom clusters in these patients are limited, the purpose of this study, in breast cancer patients undergoing CTX (n = 515), was to identify whether the number and types of symptom clusters differed based on whether symptom occurrence rates or symptom severity ratings were used to create the clusters.
methodsA modified version of the Memorial Symptom Assessment Scale was used to assess for the occurrence and severity of 38 symptoms, one week after the administration of CTX. Exploratory factor analysis was used to extract the symptom clusters.
resultsBoth the number and types of symptom clusters were similar using symptom occurrence rates or symptom severity ratings. Five symptom clusters were identified using symptom occurrence rates (i.e., psychological, hormonal, nutritional, gastrointestinal, epithelial). Six symptom clusters (i.e., psychological, hormonal, nutritional, gastrointestinal, epithelial, chemotherapy neuropathy) were identified using symptom severity ratings. Across the two dimensions, the specific symptoms within each of the symptom clusters were similar.
conclusionsIdentification of symptom clusters in patients with breast cancer may be useful in guiding symptom management interventions. Future studies are warranted to determine if symptom clusters remain stable over a cycle of CTX in patients with breast cancer.
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