ArticleClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2017
Maternal colonization with Staphylococcus aureus and Group B streptococcus is associated with colonization in newborns.
Article in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- A Systemic Review and Meta-analysis of the Leading Pathogens Causing Neonatal Sepsis in Developing Countries.BioMed research international · 2021Pooled it
- Streptococcus agalactiae maternal colonization, antibiotic resistance and serotype profiles in Africa: a meta-analysis.Annals of clinical microbiology and antimicrobials · 2019Pooled it
- Streptococcus agalactiae colonization is common among pregnant women with HIV infection and is neither predicted by hospital tier nor trimester in Mwanza, Tanzania.BMC pregnancy and childbirth · 2025Article
- Molecular Epidemiology Clinical Manifestations, Decolonization Strategies, and Treatment Options of Methicillin-ResistantPathogens (Basel, Switzerland) · 2025Review
- Group B streptococcus in pregnant women and neonates in Africa: a scoping review.BMJ public health · 2025Article
- Genomic approach to determine sources of neonatal Staphylococcus aureus infection from carriage in the Gambia.BMC infectious diseases · 2024Article
- Atopic Dermatitis: Fertility, Pregnancy, and Treatment Perspectives.American journal of clinical dermatology · 2024Review
- Guillain-Barre syndrome complicating knee infectious arthritis.Clinical case reports · 2023Article
- Review
- Gardnerella vaginalis promotes group B Streptococcus vaginal colonization, enabling ascending uteroplacental infection in pregnant mice.American journal of obstetrics and gynecology · 2021Article
- Emerging serotype III sequence type 17 group B streptococcus invasive infection in infants: the clinical characteristics and impacts on outcomes.BMC infectious diseases · 2019Article
- Newborn colonization and antibiotic susceptibility patterns of Streptococcus agalactiae at the University of Gondar Referral Hospital, Northwest Ethiopia.BMC pediatrics · 2018Article
- Protective effect of Group B Streptococcus type-III polysaccharide conjugates against maternal colonization, ascending infection and neonatal transmission in rodent models.Scientific reports · 2018Article
- A prospective cohort study ofInfection and drug resistance · 2018Article
- Maternal-Infant Correlation of Multidrug-ResistantFrontiers in pediatrics · 2018Article
- New Threats from an Old Foe: Methicillin-Resistant Staphylococcus aureus Infections in Neonates.Neonatology · 2018Review
- Methicillin resistant staphylococcus aureus infection in neonates- a major concern and a call for action.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
- Distribution of group B streptococci serotypes on women nasopharynx.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 3 countries.
Funding
Abstract
objectivesAlthough Staphylococcus aureus and Group B streptococcus (GBS) are major causes of neonatal sepsis in sub-Saharan Africa, it is unclear how these bacteria are transmitted to the neonate.
methodsIn a cohort of 377 Gambian women and their newborns, nasopharyngeal swabs were collected at delivery (day 0), and 3, 6, 14 and 28 days later. Breast milk samples and vaginal swabs were collected from the mother. Staphylococcus aureus and GBS were isolated using conventional microbiological methods.
resultsMost women were carriers of S. aureus (264 out of 361 with all samples collected, 73.1%) at some point during follow up and many were carriers of GBS (114 out of 361, 31.6%). Carriage of S. aureus was common in all three maternal sites and GBS was common in the vaginal tract and breast milk. Among newborns, carriage of S. aureus peaked at day 6 (238 out of 377, 63.1%) and GBS at day 3 (39 out of 377, 10.3%). Neonatal carriage of S. aureus at day 6 was associated with maternal carriage in the breast milk adjusted OR 2.54; 95% CI 1.45-4.45, vaginal tract (aOR 2.55; 95% CI 1.32-4.92) and nasopharynx (aOR 2.49; 95% CI 1.56-3.97). Neonatal carriage of GBS at day 6 was associated with maternal carriage in the breast milk (aOR 3.75; 95% CI 1.32-10.65) and vaginal tract (aOR 3.42; 95% CI 1.27-9.22).
conclusionsMaternal colonization with S. aureus or GBS is a risk factor for bacterial colonization in newborns.
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Registered trials
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