Evidence map›Paper›PMID 28477628›Full record

ArticleBMC infectious diseases2017

Epidemiology of Candida albicans and non-C.albicans of neonatal candidemia at a tertiary care hospital in western China.

Jinjian Fu, Yanling Ding, Ba Wei, Lin Wang, Shaolin Xu, Peixu Qin, Liuhua Wei, Lijun Jiang

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Review
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  17. Physiological and transcriptome analysis ofFrontiers in cellular and infection microbiology · 2023
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  18. An intestinalVeterinary world · 2022
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jinjian FuDepartment of Laboratory, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou, China.
Yanling DingDepartment of Laboratory, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou, China.
Ba WeiDepartment of Neonatology, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou, China.
Lin WangDepartment of Science and Education, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou, China.
Shaolin XuDepartment of Laboratory, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou, China.
Peixu QinDepartment of Laboratory, Liuzhou Maternity and Child Healthcare Hospital, Liuzhou, China.
Liuhua WeiDepartment of Laboratory, Liuzhou Worker's Hospital, No 1 Liushi Rd, Liuzhou, 545005, China. weiliuhua2005@163.com.
Lijun JiangDepartment of Laboratory, Liuzhou Worker's Hospital, No 1 Liushi Rd, Liuzhou, 545005, China. jljlzgy@126.com.
Liuzhou Maternal and Child Health Hospital · CNFourth Affiliated Hospital of Guangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough the majority of Candida infections occur in the developing world, candidemia epidemiology is poorly understood in these countries. The aim of this study was to investigate the epidemiology of non-Candida albicans (non-C. albicans) candidemia among neonates at Liuzhou Maternity and Child Healthcare Hospital in China.

methodsA retrospective review of all positive blood culture about Candida species in neonatal intensive care unit was conducted between January 2012 and November 2015. Information about demographics, risk factors and outcome of candidemia were collected. Univariate and multivariate logistic regression models were used to identify the risk factors associated with the development of non-C.albicans candidemia.

resultsThe prevalence of candidemia in infants was 1.4%. Non-C.albicans was responsible for 56.5% of neonatal candidemia. The predisposing factors for development of non-C.albicans candidemia among infants included mechanical ventilation [odds ratio (OR), 95% confidence interval (95%CI) = 3.13, 1.07-9.14; P = 0.037] and use of assisted reproductive technology (OR, 95%CI = 4.52, 1.39-14.77; P = 0.012). The overall mortality rate of candidemia was 8.7% and non-C.albicans attributed to 83.3% of all mortalities.

conclusionsNon-C.albicans species are the major cause of candidemia in local neonatal group. The study highlights the urgent needs to evaluate the possibility of development of non-C.albicans candidemia in neonates exposed to these risk factors and much emphasis must be laid on the early implementation of medical intervention to reduce the incidences of candidemia in neonates.

Indexed as

CandidaCandida albicansCandidemiaChinaHumansInfantInfant, NewbornIntensive Care Units, NeonatalLogistic ModelsRespiration, ArtificialRetrospective StudiesRisk FactorsTertiary Care CentersAssisted reproductive technologyCandidemiaInfantsNon-C.albicans

Identifiers

PMID28477628
PMCPMC5420153
OpenAlexW2611615560

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.