ArticleInternational urology and nephrology2017
Association between multiple chronic conditions and urolithiasis.
Article in International urology and nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Urolithiasis Prevalence and Associated Factors Among Adult Outpatients in Addis Ababa, Ethiopia: A Cross-Sectional Study.BioMed research international · 2026Article
- The global, regional, and national burden of urolithiasis in 204 countries and territories, 2000-2021: a systematic analysis for the Global Burden of Disease Study 2021.EClinicalMedicine · 2024Article
- An exploratory study evaluated the 30 most commonly reported medications in the United States food and drug administration's adverse event reporting system that are associated with the occurrence of kidney stones.Frontiers in pharmacology · 2024Article
- Scoping Review of Employer-Led Research Using Employee Health Claims Data.Population health management · 2023Article
- A nomogram for predicting the risk of residual stone fragments after ureteroscopy.Translational andrology and urology · 2023Article
- Causal effects of circulating lipids and lipid-lowering drugs on the risk of urinary stones: a Mendelian randomization study.Frontiers in endocrinology · 2023Article
- [Epidemiology and diagnosis of urinary lithiasis: a cross-sectional study in a Cameroonian based population].The Pan African medical journal · 2023Observational
- Dyslipidemia Increases the Risk of Incident Kidney Stone Disease in a Large Taiwanese Population Follow-Up Study.Nutrients · 2022Article
- Frailty predicts a higher risk of incident urolithiasis in 525 368 patients with diabetes mellitus: a population-based study.BMJ open diabetes research & care · 2020Article
- Prevalence of hypertension and diabetes after exposure to extracorporeal shock-wave lithotripsy in patients with renal calculi: a retrospective non-randomized data analysis.International urology and nephrology · 2018Article
- Prevalence, pathophysiological mechanisms and factors affecting urolithiasis.International urology and nephrology · 2018Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeGiven the risk factors for stone disease, it is possible that multiple chronic condition (MCC) patients are at increased risk of developing new, recurrent, or worsening urolithiasis. The purpose of our investigation was to evaluate the relationship between MCCs and urolithiasis.
methodsRetrospective cohort using outpatient claims data for all adult members (≥18 years) of the Beaumont Employee Health Plan who received outpatient care between 2008 and 2013. Multiple logistic regression adjusted for age, sex, obesity, hyperlipidemia, hypertension, and diabetes was used to assess the relationship between number of comorbid chronic conditions and urolithiasis.
resultsThe cohort consisted of 34,173 adult patients with an average age of 40.4 years and 61.2% being female. The prevalence of urolithiasis was 3.1% (n = 1059). Patients with urolithiasis had a significantly higher average number of comorbid chronic conditions (2.4 vs. 1.3, p < 0.001) than patient without urolithiasis. Both crude (OR 1.34; 95% CI 1.30-1.38) and adjusted logistic regression models (OR 1.37; 95% CI 1.31-1.44) revealed a significant relationship between number of comorbid chronic conditions and urolithiasis. More than 81% of patients had one or more co-occurring chronic conditions; the most common MCC combinations associated with urolithiasis were hypertension-hyperlipidemia, chronic back pain, and hyperlipidemia.
conclusionWe report an association between MCCs and urolithiasis. Future research is needed to better understand the temporality and strength of this relationship. Physicians should recognize that urolithiasis and MCCs are closely related and therefore may consider more aggressive primary prevention of chronic disease and improved management of MCCs.
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