Evidence map›Paper›PMID 28477231›Full record

ArticleJournal of biomolecular NMR2017

Comparison of the free and ligand-bound imino hydrogen exchange rates for the cocaine-binding aptamer.

Zachary R Churcher, Miguel A D Neves, Howard N Hunter, Philip E Johnson

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of biomolecular NMR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zachary R ChurcherDepartment of Chemistry and Centre for Research on Biomolecular Interactions, York University, Toronto, ON, M3J 1P3, Canada.
Miguel A D NevesDepartment of Chemistry and Centre for Research on Biomolecular Interactions, York University, Toronto, ON, M3J 1P3, Canada.
Howard N HunterDepartment of Chemistry and Centre for Research on Biomolecular Interactions, York University, Toronto, ON, M3J 1P3, Canada.
Philip E JohnsonDepartment of Chemistry and Centre for Research on Biomolecular Interactions, York University, Toronto, ON, M3J 1P3, Canada. pjohnson@yorku.ca.ORCID http://orcid.org/0000-0002-5573-4891

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using NMR magnetization transfer experiments, the hydrogen exchange rate constants (k

Indexed as

Aptamers, NucleotideBase SequenceBinding SitesCocaineHydrogenLigandsMagnetic Resonance SpectroscopyNucleic Acid ConformationQuinineAptamers, NucleotideCocaineHydrogenLigandsQuinineAptamer functionDNA-small molecule interactionsHydrogen exchange rate constantLigand binding

Identifiers

PMID28477231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.