Evidence map›Paper›PMID 28477099›Full record

ReviewParasitology research2017

Nanomedicine advances in toxoplasmosis: diagnostic, treatment, and vaccine applications.

João Paulo Assolini, Virginia Márcia Concato, Manoela Daiele Gonçalves, Amanda Cristina Machado Carloto, Ivete Conchon-Costa, Wander Rogério Pavanelli, Francine Nesello Melanda, Idessania Nazareth Costa

Abstract readReview
PubMed Publisher
In one paragraph

Review in Parasitology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 55 citations in OpenAlex.

  1. Anti-Advanced biomedical research · 2026
    Article
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  7. Article
  8. Review
  9. Article
  10. Anti-Food science & nutrition · 2024
    Article
  11. Review
  12. Nanoformulation-Based 1,2,3-Triazole Sulfonamides for Anti-Tropical medicine and infectious disease · 2023
    Article
  13. Nanoemulsion of Spiramycin against Tachyzoites ofIranian journal of public health · 2023
    Article
  14. Review
  15. Nano magnetic-based ELISA and nano magnetic-based latex agglutination test for diagnosis of experimental trichinellosis.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Remarkable histopathological improvement of experimental toxoplasmosis after receiving spiramycin-chitosan nanoparticles formulation.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

João Paulo AssoliniDepartamento de Ciências Patológicas, Laboratório de Parasitologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Virginia Márcia ConcatoDepartamento de Ciências Patológicas, Laboratório de Parasitologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Manoela Daiele GonçalvesDepartamento de Ciências Patológicas, Laboratório de Parasitologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Amanda Cristina Machado CarlotoDepartamento de Ciências Patológicas, Laboratório de Parasitologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Ivete Conchon-CostaDepartamento de Ciências Patológicas, Laboratório de Parasitologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Wander Rogério PavanelliDepartamento de Ciências Patológicas, Laboratório de Parasitologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Francine Nesello MelandaDepartamento de Ciências Patológicas, Laboratório de Parasitologia, Universidade Estadual de Londrina, Londrina, PR, Brazil.
Idessania Nazareth CostaDepartamento de Ciências Patológicas, Laboratório de Parasitologia, Universidade Estadual de Londrina, Londrina, PR, Brazil. idessania@hotmail.com.
Universidade Estadual de Londrina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasmosis is an infectious disease caused by the intracellular parasite Toxoplasma gondii that affects about one third of the world's population. The diagnosis of this disease is carried out by parasite isolation and host antibodies detection. However, the diagnosis presents problems in regard to test sensitivity and specificity. Currently, the most effective T. gondii treatment is a combination of pyrimethamine and sulfadiazine, although both drugs are toxic to the host. In addition to the problems that compromise the effective diagnosis and treatment of toxoplasmosis, there are no reports or indications of any vaccine capable of fully protecting against this infection. Nanomaterials, smaller than 1000 nm, are currently being investigated as an alternative tool in the management of T. gondii infection. This article reviews how recent nanotechnology advances indicate the utility of nanomaterials in toxoplasmosis diagnosis, treatment, and vaccine development.

Indexed as

AnimalsHumansNanostructuresProtozoan VaccinesToxoplasmaToxoplasmosisProtozoan VaccinesInfectionNanomedicineNanoparticlesNanotechnologyToxoplasma gondii

Identifiers

PMID28477099
OpenAlexW2611789293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.