Evidence map›Paper›PMID 28477086›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2017

Effects of salvianolic acid B on L-type calcium channels and myocardial contractility in isolated rat ventricular myocytes and hERG K

Qiongtao Song, Xue Han, Yuchong Xue, Tao Song, Xi Chu, Xuan Zhang, Yuanyuan Zhang, Ying Zhang, Jianping Zhang, Li Chu

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Qiongtao SongHebei University of Chinese Medicine, No. 3, Xingyuan Road, Shijiazhuang, Hebei, 050200, China.
Xue HanHebei University of Chinese Medicine, No. 3, Xingyuan Road, Shijiazhuang, Hebei, 050200, China.
Yuchong XueHebei University of Chinese Medicine, No. 3, Xingyuan Road, Shijiazhuang, Hebei, 050200, China.
Tao SongHebei University of Chinese Medicine, No. 3, Xingyuan Road, Shijiazhuang, Hebei, 050200, China.
Xi ChuThe Fourth Hospital of Hebei Medical University, No. 12, Jiankang Road, Shijiazhuang, Hebei, 050011, China.
Xuan ZhangHebei University of Chinese Medicine, No. 3, Xingyuan Road, Shijiazhuang, Hebei, 050200, China.
Yuanyuan ZhangHebei University of Chinese Medicine, No. 3, Xingyuan Road, Shijiazhuang, Hebei, 050200, China.
Ying ZhangHebei University of Chinese Medicine, No. 3, Xingyuan Road, Shijiazhuang, Hebei, 050200, China.
Jianping ZhangHebei University of Chinese Medicine, No. 3, Xingyuan Road, Shijiazhuang, Hebei, 050200, China. zhangjianping14@126.com.
Li ChuHebei University of Chinese Medicine, No. 3, Xingyuan Road, Shijiazhuang, Hebei, 050200, China. chuli0614@126.com.
Hebei University of Chinese Medicine · CNHebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salvianolic acid B (Sal B), one of the chief water-soluble constituents in Radix Salviae Milthiorrhizae, has often been reported to possess considerable cardiovascular regulatory effects. However, the underlying biochemical and cellular mechanisms of its cardioprotection remain unclear. This study was designed to evaluate the role of Sal B regulation in L-type Ca

Indexed as

AnimalsBenzofuransCalciumCalcium Channels, L-TypeCardiotonic AgentsDepsidesEther-A-Go-Go Potassium ChannelsHeart VentriclesHEK293 CellsHumansMyocardial ContractionMyocytes, CardiacRats, Sprague-DawleyBenzofuransCalciumCalcium Channels, L-TypeCardiotonic AgentsDepsidesEther-A-Go-Go Potassium Channelssalvianolic acid BCalcium overloadDrug-induced long QT syndromeL-type calcium currentMyocardial contractilityRapidly activating delayed rectifier potassium currentSalvianolic acid B

Identifiers

PMID28477086
OpenAlexW2611475148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.