Evidence map›Paper›PMID 28476308›Full record

ArticleMagnetic resonance imaging2017

Magnetic resonance elastography of the pancreas: Measurement reproducibility and relationship with age.

Arunark Kolipaka, Samuel Schroeder, Xiaokui Mo, Zarine Shah, Phil A Hart, Darwin L Conwell

Abstract read
In one paragraph

Article in Magnetic resonance imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Nutrients · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Advances in MRI of Chronic Pancreatitis.Advances in clinical radiology · 2024
    Article
  12. Cross-sectional imaging of the pancreas in diabetes.Abdominal radiology (New York) · 2024
    Review
  13. Article
  14. Changes in Pancreatic Senescence Mediate Pancreatic Diseases.International journal of molecular sciences · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Advanced MR Imaging of the Pancreas.Magnetic resonance imaging clinics of North America · 2020
    Review
  19. Article
  20. Advanced imaging techniques for chronic pancreatitis.Abdominal radiology (New York) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Arunark KolipakaDepartment of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH, United States; Department of Internal Medicine-Division of Cardiovascular Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, United States. Electronic address: arunark.kolipaka@osumc.edu.
Samuel SchroederDepartment of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH, United States; Department of Mechanical Engineering, The Ohio State University, Columbus, OH, United States.
Xiaokui MoCenter for Biostatistics, Department of Biomedical Informatics, The Ohio State University, Columbus, OH, United States.
Zarine ShahDepartment of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Phil A HartDivision of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Darwin L ConwellDivision of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
The Ohio State University Wexner Medical Center · USThe Ohio State University · US

Funding

The Ohio State University Center for Clinical and Translational Science (UL1)UL1TR000090 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2012 to 2013
$7.9M
The Ohio State University Pancreatic Disorders Network (OSU-PDN)U01DK108327 · NIDDK · OHIO STATE UNIVERSITY · PI CONWELL, DARWIN LEWIS, HART, PHILIP A. · 2015 to 2024
$5.5M
Improved Understanding of Abdominal Aortic Aneurysm Progression using MR ElastographyR01HL124096 · NHLBI · OHIO STATE UNIVERSITY · PI KOLIPAKA, ARUNARK · 2015 to 2019
$2.4M
American Heart Association-American Stroke Association 13SDG14690027NCATS NIH HHS UL1 TR000090NHLBI NIH HHS R01 HL124096NIDDK NIH HHS U01 DK108327
6 · The paper itself

Abstract

purposeTo determine magnetic resonance elastography (MRE)-derived stiffness of pancreas in healthy volunteers with emphasis on: 1) short term and midterm repeatability; and 2) variance as a function of age.

methodsPancreatic MRE was performed on 22 healthy volunteers (age range:20-64years) in a 3T-scanner. For evaluation of reproducibility of stiffness estimates, the scans were repeated per volunteer on the same day (short term) and one month apart (midterm). MRE wave images were analyzed using 3D inversion to estimate the stiffness of overall pancreas and different anatomic regions (i.e., head, neck, body, and tail). Concordance and Spearman correlation tests were performed to determine reproducibility of stiffness measurements and relationship to age.

resultsA strong concordance correlation (ρ

conclusionMRE-derived pancreatic stiffness measurements are highly reproducible in the short and midterm and increase linearly with age in healthy volunteers. Further studies are needed to examine these effects in patients with various pancreatic diseases to understand potential clinical applications.

Indexed as

AdultAge FactorsAgingElasticity Imaging TechniquesFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPancreasReference ValuesReproducibility of ResultsYoung AdultMR elastography of pancreasPancreas stiffnessPancreatic MRE

Identifiers

PMID28476308
PMCPMC5581721
OpenAlexW2611013130

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.