ReviewEndocrinology and metabolism clinics of North America2017
Genetics of Adrenocortical Development and Tumors.
Review in Endocrinology and metabolism clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Laparoscopic Adrenalectomy: Tailoring Approaches for the Optimal Resection of Adrenal Tumors.Diagnostics (Basel, Switzerland) · 2023Article
- Adrenocortical carcinoma in a 10-month-old infant: A literature review and a rare case report.Annals of medicine and surgery (2012) · 2023Article
- Coincidence of primary adrenocortical carcinoma and melanoma: three CASE reports.BMC endocrine disorders · 2023Article
- Wnt/β-catenin signaling pathway in the tumor progression of adrenocortical carcinoma.Frontiers in endocrinology · 2023Review
- Pathological and Genetic Stratification for Management of Adrenocortical Carcinoma.The Journal of clinical endocrinology and metabolism · 2022Review
- Feminizing adrenocortical adenoma in a girl from a resource-limited setting: a case report.Journal of medical case reports · 2021Article
- The Role of Biomarkers in Adrenocortical Carcinoma: A Review of Current Evidence and Future Perspectives.Biomedicines · 2021Review
- Medical Approaches in Adrenocortical Carcinoma.Biomedicines · 2020Review
- Adrenocortical carcinoma in a young adult male with chronic urticaria: A case report and literature review.International journal of surgery case reports · 2020Article
- Nutlin-3a as a novel anticancer agent for adrenocortical carcinoma with CTNNB1 mutation.Cancer medicine · 2018Article
- Coincidence of Intracranial Myoepithelioma and Adrenocortical Carcinoma in a Young Man.Asian journal of neurosurgeryArticle
- ADRENOCORTICAL CARCINOMA: IN THE SEARCH FOR A PRE-OPERATIVE BIOMARKER.Acta endocrinologica (Bucharest, Romania : 2005)Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
This article links the understanding of developmental physiology of the adrenal cortex to adrenocortical tumor formation. Many molecular mechanisms that lead to formation of adrenocortical tumors have been discovered via next-generation sequencing approaches. The most frequently mutated genes in adrenocortical tumors are also factors in normal adrenal development and homeostasis, including those that alter the p53 and Wnt/β-catenin pathways. In addition, dysregulated protein kinase A signaling and ARMC5 mutations have been identified as key mediators of adrenocortical tumorigenesis. The growing understanding of genetic changes that orchestrate adrenocortical development and disease pave the way for potential targeted treatment strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.