ArticleJournal of dental research2017
Association of Condylar Bone Quality with TMJ Osteoarthritis.
Article in Journal of dental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Orthognathic surgery-related condylar resorption in patients with skeletal class III malocclusion versus class III malocclusion: a systematic review and meta-analysis.BMC oral health · 2025Pooled it
- Demographic and structural indicators of temporomandibular joint osteoarthritis in asymptomatic adults: a cone-beam computed tomography-based multivariate analysis.Oral radiology · 2026Article
- Temporomandibular joint (TMJ) morphology in jaw deformity patients (class II and III) before and after surgical orthodontic treatment: a narrative review.Maxillofacial plastic and reconstructive surgery · 2026Review
- Osteocyte-Intrinsic MMP13 exacerbates injury-induced temporomandibular joint osteoarthritis.Osteoarthritis and cartilage · 2026Article
- Mandibular condyle bone density and cortical bone thickness in subjects affected by juvenile idiopathic arthritis assessed with cone-beam computed tomography: a cross-sectional study.BMC oral health · 2026Article
- Engineered Nanomaterials for Drug Delivery in Temporomandibular Joint Osteoarthritis: Translational Insights and Current Advances.International journal of nanomedicine · 2026Review
- Goat temporomandibular joint osteochondral defects for future regenerative studies of osteoarthritis-like degeneration.PloS one · 2026Article
- Comparison of the maximum standardized uptake value and magnetic resonance imaging characteristics between temporomandibular joint osteoarthrosis and osteoarthritis.Scientific reports · 2025Article
- Association between condylar surface computed tomography values in the coronal plane and temporomandibular joint disc position in jaw deformity patients: a retrospective study.Oral and maxillofacial surgery · 2024Article
- Osteoarthritic Bony Alterations of Temporomandibular Joint and Relation to Low Bone Mineral Density in Postmenopausal Edentulous Females.Dentistry journal · 2024Article
- Long-term haplodeficency of DSPP causes temporomandibular joint osteoarthritis in mice.BMC oral health · 2024Article
- A study on volumetric change of mandibular condyles with osteoarthritis using cone-beam computed tomography.Scientific reports · 2024Article
- Evaluation of the mandibular condylar bone microarchitecture in people living with HIV.Oral diseases · 2024Article
- Osteoarthritis Diagnosis Integrating Whole Joint Radiomics and Clinical Features for Robust Learning Models Using Biological Privileged Information.Medical image computing and computer assisted intervention - MICCAI 2023 workshops : ISIC 2023, Care-AI 2023, MedAGI 2023, DeCaF 2023, held in conjunction with MICCAI 2023, Vancouver, BC, Canada, October 8-12, 2023, proceedings · 2023Article
- Comparison of the efficacy of intra-articular injections of hyaluronic acid and lactoferrin in mono-iodoacetate-induced temporomandibular joint osteoarthritis: A histomorphometric, immunohistochemistry, and micro-computed tomography analysis.Joint diseases and related surgery · 2023Article
- Temporomandibular Disorders and Vitamin D Deficiency: What Is the Linkage between These Conditions? A Systematic Review.Journal of clinical medicine · 2022Review
- Morphologic and histologic characterization of sheep and porcine TMJ as large animal models for tissue engineering applications.Clinical oral investigations · 2022Article
- Antisense Oligonucleotide-Based Therapy on miR-181a-5p Alleviates Cartilage Degradation of Temporomandibular Joint OsteoarthritisFrontiers in pharmacology · 2022Article
- Mitochondria-targeted supramolecular coordination container encapsulated with exogenous itaconate for synergistic therapy of joint inflammation.Theranostics · 2022Article
- Bone mineral density, bone microstructure, and bone turnover markers in females with temporomandibular joint osteoarthritis.Clinical oral investigations · 2021Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
The etiology and treatment of temporomandibular joint (TMJ) osteoarthritis (TMJOA) remain complex and unclear. Based on clinical observations, we hypothesized that low condylar bone quality is significantly correlated with TMJOA and explored this association in a cross-sectional study with human patients. A total of 254 postmenopausal female participants were included in this study. Radiographic findings from cone beam computed tomography (CBCT) and clinical symptoms were used to classify each TMJ data sample as healthy control ( n = 124) or TMJOA ( n = 130). Condylar bone mineral density (BMD) (computed tomography Hounsfield unit [CT HU]) and bone volume fraction (BV/TV) were measured and modeled as predictors of healthy control versus TMJOA status in multilevel logistic regression analyses. Both CT HU (adjusted odds ratio [AOR] = 0.9989, interquartile odds ratio [IOR] = 0.4206) and BV/TV (AOR= 0.8096, IOR = 0.1769) were negatively associated with TMJOA ( P = 0.049, 0.011, respectively). To assess the diagnostic performance of CT HU and BV/TV for identification of TMJOA, receiver operating characteristic (ROC) curves were plotted. The estimated areas under the curve (AUC) were 0.6622 for BV/TV alone, 0.6074 for CT HU alone, and 0.7136 for CT HU and BV/TV together. The model incorporating CT HU and BV/TV together had a significantly higher AUC than the models using BV/TV alone ( P = 0.038) or HU alone ( P = 0.021). In conclusion, we found that low condylar bone quality was significantly correlated with TMJOA development and that condylar CT HU and BV/TV can be used together as a potential diagnostic tool for TMJOA. Careful clinical evaluation of the condyle coupled with appropriate radiographic interpretation would thus be critical for the early detection of TMJOA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.