Evidence map›Paper›PMID 28476089›Full record

ArticleNanoscale research letters2017

Antitumor Activity of Alloy and Core-Shell-Type Bimetallic AgAu Nanoparticles.

Igor Shmarakov, Iuliia Mukha, Nadiia Vityuk, Vira Borschovetska, Nelya Zhyshchynska, Galyna Grodzyuk, Anna Eremenko

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanoscale research letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 60 citations in OpenAlex.

  1. Nanotechnology Meets Immunotherapy: Crosstalks Against Cancer.Immunity, inflammation and disease · 2026
    Review
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  15. Metallic Nanoparticles for Cancer Immunotherapy.Materials today (Kidlington, England)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Igor ShmarakovDepartment of Biochemistry and Biotechnology, Yuriy Fedkovych Chernivtsi National University, Kotsuybynskyiy St., 2, Chernivtsi, 58012, Ukraine. igor.shmarakov@gmail.com.ORCID http://orcid.org/0000-0002-4073-9585
Iuliia MukhaLaboratory of Photonics of Nanosized Oxide Systems, Chuiko Institute of Surface Chemistry, National Academy of Sciences of Ukraine, General Naumov St., 17, Kyiv, 03164, Ukraine.
Nadiia VityukLaboratory of Photonics of Nanosized Oxide Systems, Chuiko Institute of Surface Chemistry, National Academy of Sciences of Ukraine, General Naumov St., 17, Kyiv, 03164, Ukraine.
Vira BorschovetskaDepartment of Biochemistry and Biotechnology, Yuriy Fedkovych Chernivtsi National University, Kotsuybynskyiy St., 2, Chernivtsi, 58012, Ukraine.
Nelya ZhyshchynskaDepartment of Biochemistry and Biotechnology, Yuriy Fedkovych Chernivtsi National University, Kotsuybynskyiy St., 2, Chernivtsi, 58012, Ukraine.
Galyna GrodzyukL.V. Pisarzhevskii Institute of the Physical Chemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine.
Anna EremenkoLaboratory of Photonics of Nanosized Oxide Systems, Chuiko Institute of Surface Chemistry, National Academy of Sciences of Ukraine, General Naumov St., 17, Kyiv, 03164, Ukraine.
National Academy of Sciences of Ukraine · UAYuriy Fedkovych Chernivtsi National University · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticles (NPs) of noble metals, namely gold and silver, remain promising anticancer agents capable of enhancing current surgery- and chemotherapeutic-based approaches in cancer treatment. Bimetallic AgAu composition can be used as a more effective agent due to the synergetic effect. Among the physicochemical parameters affecting gold and silver nanoparticle biological activity, a primary concern relates to their size, shape, composition, charge, etc. However, the impact of metal components/composition as well as metal topological distribution within NPs is incompletely characterized and remains to be further elucidated and clarified. In the present work, we tested a series of colloidal solutions of AgAu NPs of alloy and core-shell type for an antitumor activity depending on metal molar ratios (Ag:Au = 1:1; 1:3; 3:1) and topological distribution of gold and silver within NPs (Au

Indexed as

Anticancer activityGoldNanoparticlesOxidative stressSilver

Identifiers

PMID28476089
PMCPMC5418356
OpenAlexW2611764813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.