Evidence map›Paper›PMID 28476066›Full record

ReviewSeminars in thrombosis and hemostasis2017

Angiodysplasia in von Willebrand Disease: Understanding the Clinical and Basic Science.

Soundarya Selvam, Paula James

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Seminars in thrombosis and hemostasis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06050798 (Hematological Disorder in Patients With Angiodysplasia), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06050798 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Hematological Disorder in Patients With Angiodysplasia

TypeobservationalSponsorAssiut UniversityRan2024 to 2026Enrolled55ConditionsAngiodysplasia, Hematological DiseaseArmsVon willebrand antigen
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Special considerations in GI bleeding in VWD patients.Hematology. American Society of Hematology. Education Program · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Soundarya SelvamDepartment of Pathology and Molecular Medicine, Queen's University, Kingston, Canada.
Paula JamesDepartment of Pathology and Molecular Medicine, Queen's University, Kingston, Canada.
Queen's University · CA

Funding

Zimmerman Program for the Molecular and Clinical Biology of VWDP01HL081588 · NHLBI · VERSITI WISCONSIN, INC. · PI MONTGOMERY, ROBERT R · 2005 to 2016
$19.3M
NHLBI NIH HHS P01 HL081588
6 · The paper itself

Abstract

Severe and intractable gastrointestinal bleeding caused by angiodysplasia is a debilitating problem for up to 20% of patients with von Willebrand disease (VWD). Currently, the lack of an optimal treatment for this recurrent problem presents an ongoing challenge for many physicians in their management of affected patients. Over the past few years, studies have pointed to a regulatory role for the hemostatic protein, von Willebrand factor (VWF), in angiogenesis, providing a novel target for the modulation of vessel development. This article will review the clinical implications and molecular pathology of angiodysplasia in VWD.

Indexed as

Angiodysplasiavon Willebrand DiseasesHumansvon Willebrand Factorvon Willebrand Factor

Identifiers

PMID28476066
PMCPMC5949878
OpenAlexW2611224701

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.