Evidence map›Paper›PMID 28475928›Full record

ArticleJournal of chromatography. B, Analytical technologies in the biomedical and life sciences2017

Development and characterization of mitochondrial membrane affinity chromatography columns derived from skeletal muscle and platelets for the study of mitochondrial transmembrane proteins.

Nagendra Surendra Singh, Kaia-Liisa Habicht, Ruin Moaddel, Ruth Shimmo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Nagendra Surendra SinghBiomedical Research Center, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Suite 100, 21224 Baltimore, MD, USA.
Kaia-Liisa HabichtBiomedical Research Center, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Suite 100, 21224 Baltimore, MD, USA; School of Natural Sciences and Health, Tallinn University, Narva mnt 29, 10120 Tallinn, Estonia.
Ruin MoaddelBiomedical Research Center, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Suite 100, 21224 Baltimore, MD, USA.
Ruth ShimmoSchool of Natural Sciences and Health, Tallinn University, Narva mnt 29, 10120 Tallinn, Estonia. Electronic address: ruth.shimmo@tlu.ee.
Tallinn University · EENational Institute on Aging · USNational Institutes of Health · US

Funding

Immobilized Receptors In Drug DiscoveryZIAAG000295 · NIA · NATIONAL INSTITUTE ON AGING · PI EGAN, JOSEPHINE · 2009 to 2025
$11.4M
Intramural NIH HHS Z99 AG999999Intramural NIH HHS ZIA AG000295
6 · The paper itself

Abstract

Mitochondrial membrane fragments from human platelets and monkey skeletal muscles were successfully immobilized onto immobilized artificial membrane chromatographic support for the first time, resulting in mitochondrial membrane affinity chromatography (MMAC) columns. These columns were validated by characterization of translocator protein (TSPO), where multiple concentrations of dipyridamole were run and the binding affinities (K

Indexed as

AnimalsBlood PlateletsChromatography, AffinityHumansImmobilized ProteinsLigandsMacaca mulattaMaleMitochondrial MembranesMitochondrial ProteinsMitochondrial Proton-Translocating ATPasesMuscle, SkeletalReceptors, GABAImmobilized ProteinsLigandsMitochondrial ProteinsMitochondrial Proton-Translocating ATPasesReceptors, GABATSPO protein, humanATPaseATP synthaseMitochondrial membrane affinity chromatographyPlateletsSkeletal muscleTranslocator protein

Identifiers

PMID28475928
PMCPMC5977994
OpenAlexW2605481723

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.