Evidence map›Paper›PMID 28475835›Full record

ArticleThe journal of physical chemistry. B2017

Mean Direct-Transit and Looping Times as Functions of the Potential Shape.

Alexander M Berezhkovskii, Leonardo Dagdug, Sergey M Bezrukov

Abstract read
In one paragraph

Article in The journal of physical chemistry. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Time and Length Scales of Incomplete Translocation through Nanopores.The journal of physical chemistry letters · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alexander M BerezhkovskiiSection on Molecular Transport, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health , Bethesda, Maryland 20892, United States.
Leonardo DagdugSection on Molecular Transport, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health , Bethesda, Maryland 20892, United States.
Sergey M BezrukovSection on Molecular Transport, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health , Bethesda, Maryland 20892, United States.ORCID 0000-0002-8209-8050

Funding

Biophysics of Large Membrane ChannelsZIAHD000072 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BEZRUKOV, SERGEY M · 2009 to 2025
$22.8M
Modeling of kinetic processes in biological systemsZIACT000273 · CIT · CENTER FOR INFORMATION TECHNOLOGY · PI BEREZHKOVSKII, ALEXANDER · 2009 to 2021
$2.1M
Intramural NIH HHS ZIA CT000273
6 · The paper itself

Abstract

Any trajectory of a diffusing particle making a transition between two end points of an interval can be divided into two segments, which we call direct-transit and looping parts. The former is the final segment of the trajectory, when the particle goes from one end point of the interval to the opposite end point, without retouching the starting point. The rest of the trajectory is the looping part. We study mean durations of the two parts in the presence of a symmetric linear cusp potential which, depending on the parameter values, forms either a barrier or a well between the end points. For the cusp barrier, we find that the mean direct-transit time decreases as the barrier height increases at a fixed interval length. This happens because the increase in the barrier height results in the increase of the magnitude of the force acting on the particle on both sides of the barrier. Interestingly, though the mean looping and direct-transit times are different in the case of the barrier and well potentials with equal height and depth, respectively, the mean first-passage times for the two cases are identical.

Indexed as

Models, ChemicalThermodynamicsChemistry, Physical

Identifiers

PMID28475835
PMCPMC5580047

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.