Evidence map›Paper›PMID 28475474›Full record

ArticlemAbs2017

Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges.

Mohammed Akli Ayoub, Pascale Crépieux, Markus Koglin, Marc Parmentier, Jean-Philippe Pin, Anne Poupon, Eric Reiter, Martine Smit, Jan Steyaert, Hervé Watier and 1 more

Open access · goldAbstract read
In one paragraph

Article in mAbs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

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  12. Machine learning reveals hidden stability code in protein native fluorescence.Computational and structural biotechnology journal · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 5 countries.

Mohammed Akli Ayouba PRC, INRA, CNRS, Université François-Rabelais de Tours , Nouzilly , France.
Pascale Crépieuxa PRC, INRA, CNRS, Université François-Rabelais de Tours , Nouzilly , France.
Markus Koglind Heptares Therapeutics Ltd , BioPark, Welwyn Garden City, Hertfordshire , UK.
Marc Parmentiere Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, Université Libre de Bruxelles , Brussels , Belgium.
Jean-Philippe Ping Institut de Génomique Fonctionnelle (IGF), Université de Montpellier, CNRS UMR5203 , Montpellier , France.
Anne Poupona PRC, INRA, CNRS, Université François-Rabelais de Tours , Nouzilly , France.
Eric Reitera PRC, INRA, CNRS, Université François-Rabelais de Tours , Nouzilly , France.
Martine Smiti Amsterdam Institute for Molecules Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Vrije Universiteit , Amsterdam , The Netherlands.
Jan Steyaertj Structural Biology Brussels, Vrije Universiteit Brussels , Brussels , Belgium.
Hervé Watierl Université François-Rabelais de Tours, CNRS, UMR 7292 , Tours , France.ORCID 0000-0002-2139-4171
Trevor Wilkinsonn Antibody Discovery and Protein Engineering, MedImmune , Cambridge , UK.
Université de Tours · FRCentre National de la Recherche Scientifique · FRHeptares Therapeutics (United Kingdom) · GBRecombinant Antibody Technology (United Kingdom) · GBUniversité Libre de Bruxelles · BEVrije Universiteit Amsterdam · NLVrije Universiteit Brussel · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Le STUDIUM conference was held November 24-25, 2016 in Tours, France as a satellite workshop of the 5

Indexed as

Receptors, G-Protein-CoupledSignal TransductionSingle-Domain AntibodiesAnimalsCongresses as TopicHumansReceptors, G-Protein-CoupledSingle-Domain AntibodiesAntibodybiopharmaceuticalsGPCRG proteinnanobodyphage displayβ-arrestin

Identifiers

PMID28475474
PMCPMC5524162
OpenAlexW2610777344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.