Evidence map›Paper›PMID 28475118›Full record

ArticleInternational journal of molecular sciences2017

Effects of Gelatin Hydrogel Containing Anti-Transforming Growth Factor-β Antibody in a Canine Filtration Surgery Model.

Michiko Maeda, Shota Kojima, Tetsuya Sugiyama, Denan Jin, Shinji Takai, Hidehiro Oku, Ryohsuke Kohmoto, Mari Ueki, Tsunehiko Ikeda

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Effect of purine-rich box1 on proliferation of fibroblasts.International journal of ophthalmology · 2020
    Review
  4. Article
  5. Recent Advances in Scar Biology.International journal of molecular sciences · 2018
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Michiko MaedaDepartment of Ophthalmology, Osaka Medical College, Takatsuki-City, Osaka 569-8686, Japan. opt182@osaka-med.ac.jp.
Shota KojimaDepartment of Ophthalmology, Osaka Medical College, Takatsuki-City, Osaka 569-8686, Japan. shota@osaka-med.ac.jp.
Tetsuya SugiyamaDepartment of Ophthalmology, Osaka Medical College, Takatsuki-City, Osaka 569-8686, Japan. tsugiyama@osaka-med.ac.jp.
Denan JinDepartment of Innovative Medicine, Osaka Medical College, Takatsuki-City, Osaka 569-8686, Japan. pha012@osaka-med.ac.jp.
Shinji TakaiDepartment of Innovative Medicine, Osaka Medical College, Takatsuki-City, Osaka 569-8686, Japan. pha010@osaka-med.ac.jp.
Hidehiro OkuDepartment of Ophthalmology, Osaka Medical College, Takatsuki-City, Osaka 569-8686, Japan. opt025@osaka-med.ac.jp.
Ryohsuke KohmotoDepartment of Ophthalmology, Osaka Medical College, Takatsuki-City, Osaka 569-8686, Japan. ryousuke0218@hotmail.co.jp.
Mari UekiDepartment of Ophthalmology, Osaka Medical College, Takatsuki-City, Osaka 569-8686, Japan. opt089@osaka-med.ac.jp.
Tsunehiko IkedaDepartment of Ophthalmology, Osaka Medical College, Takatsuki-City, Osaka 569-8686, Japan. tikeda@osaka-med.ac.jp.
Osaka Medical and Pharmaceutical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this present study, we investigated the effect of a controlled release of anti-transforming growth factor β (TGF-β) antibody on intraocular pressure (IOP), bleb formation, and conjunctival scarring in a canine glaucoma filtration surgery model using gelatin hydrogel (GH). Glaucoma surgery models were made in 14 eyes of 14 beagles and divided into the following two groups: (1) subconjunctival implantation of anti-TGF-β antibody-loaded GH (GH-TGF-β group,

Indexed as

AnimalsAntibodiesDogsGelatinHydrogel, Polyethylene Glycol DimethacrylatePostoperative ComplicationsTrabeculectomyTransforming Growth Factor betaAntibodiesGelatinHydrogel, Polyethylene Glycol DimethacrylateTransforming Growth Factor betabeaglesgelatin hydrogelglaucomatrabeculectomytransforming growth factor-β

Identifiers

PMID28475118
PMCPMC5454898
OpenAlexW2610190789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.