Evidence map›Paper›PMID 28475113›Full record

ReviewBrain sciences2017

Genetic and Molecular Approaches to Study Neuronal Migration in the Developing Cerebral Cortex.

Jacobus J Dudok, Pim E G Leonards, Jan Wijnholds

Open access · goldAbstract readReview
In one paragraph

Review in Brain sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jacobus J DudokDepartment of Environment and Health, Vrije Universiteit Amsterdam, De Boelelaan 1087, Amsterdam 1081 HV, The Netherlands. j.j.dudok@vu.nl.
Pim E G LeonardsDepartment of Environment and Health, Vrije Universiteit Amsterdam, De Boelelaan 1087, Amsterdam 1081 HV, The Netherlands. pim.leonards@vu.nl.
Jan WijnholdsNetherlands Institute for Neuroscience, Meibergdreef 47, Amsterdam 1105 BA, The Netherlands. j.wijnholds@lumc.nl.
Vrije Universiteit Amsterdam · NLNetherlands Institute for Neuroscience · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The migration of neuronal cells in the developing cerebral cortex is essential for proper development of the brain and brain networks. Disturbances in this process, due to genetic abnormalities or exogenous factors, leads to aberrant brain formation, brain network formation, and brain function. In the last decade, there has been extensive research in the field of neuronal migration. In this review, we describe different methods and approaches to assess and study neuronal migration in the developing cerebral cortex. First, we discuss several genetic methods, techniques and genetic models that have been used to study neuronal migration in the developing cortex. Second, we describe several molecular approaches to study aberrant neuronal migration in the cortex which can be used to elucidate the underlying mechanisms of neuronal migration. Finally, we describe model systems to investigate and assess the potential toxicity effect of prenatal exposure to environmental chemicals on proper brain formation and neuronal migration.

Indexed as

cortexgeneticknockoutmigrationmolecularneuronprogenitor

Identifiers

PMID28475113
PMCPMC5447935
OpenAlexW2611129393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.