Evidence map›Paper›PMID 28475112›Full record

ArticleToxins2017

Insect-Active Toxins with Promiscuous Pharmacology from the African Theraphosid Spider Monocentropus balfouri.

Jennifer J Smith, Volker Herzig, Maria P Ikonomopoulou, Sławomir Dziemborowicz, Frank Bosmans, Graham M Nicholson, Glenn F King

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jennifer J SmithInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia. jennifer.smith@imb.uq.edu.au.
Volker HerzigInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia. v.herzig@imb.uq.edu.au.
Maria P IkonomopoulouInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia. maria.Ikonomopoulou@qimrberghofer.edu.au.
Sławomir DziemborowiczSchool of Life Sciences, University of Technology Sydney, NSW, Sydney 2007, Australia. slawomirdziemborowicz@gmail.com.
Frank BosmansDepartment of Physiology & Solomon H. Snyder Department of Neuroscience, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA. frankbosmans@jhmi.edu.
Graham M NicholsonSchool of Life Sciences, University of Technology Sydney, NSW, Sydney 2007, Australia. graham.nicholson@uts.edu.au.
Glenn F KingInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia. glenn.king@imb.uq.edu.au.
The University of Queensland · AUUniversity of Technology Sydney · AUJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many chemical insecticides are becoming less efficacious due to rising resistance in pest species, which has created much interest in the development of new, eco-friendly bioinsecticides. Since insects are the primary prey of most spiders, their venoms are a rich source of insect-active peptides that can be used as leads for new bioinsecticides or as tools to study molecular receptors that are insecticidal targets. In the present study, we isolated two insecticidal peptides, µ/ω-TRTX-Mb1a and -Mb1b, from venom of the African tarantula

Indexed as

SpidersAmino Acid SequenceAnimalsBiological Control AgentsCockroachesDipteraFemaleLarvaLepidopteraNeuronsPeptidesRecombinant ProteinsSpider VenomsBiological Control AgentsPeptidesRecombinant ProteinsSpider Venomscalcium channelinsecticidepharmacologysodium channelspidervenom

Identifiers

PMID28475112
PMCPMC5450703
OpenAlexW2611495940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.