Evidence map›Paper›PMID 28474844›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2017

One-Pot Synthesis of Multiple Protein-Encapsulated DNA Flowers and Their Application in Intracellular Protein Delivery.

Eunjung Kim, Limor Zwi-Dantsis, Natalie Reznikov, Catherine S Hansel, Shweta Agarwal, Molly M Stevens

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. High-throughput monitoring of free MgAnalytical and bioanalytical chemistry · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Applications of DNA-Functionalized Proteins.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Rationally Programming Nanomaterials with DNA for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  19. DNA Transformations for Diagnosis and Therapy.Advanced functional materials · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eunjung KimDepartment of Materials, Department of Bioengineering and Institute for Biomedical Engineering, Imperial College London, London, SW7 2AZ, UK.
Limor Zwi-DantsisDepartment of Materials, Department of Bioengineering and Institute for Biomedical Engineering, Imperial College London, London, SW7 2AZ, UK.
Natalie ReznikovDepartment of Materials, Department of Bioengineering and Institute for Biomedical Engineering, Imperial College London, London, SW7 2AZ, UK.
Catherine S HanselDepartment of Materials, Department of Bioengineering and Institute for Biomedical Engineering, Imperial College London, London, SW7 2AZ, UK.
Shweta AgarwalDepartment of Materials, Department of Bioengineering and Institute for Biomedical Engineering, Imperial College London, London, SW7 2AZ, UK.
Molly M StevensDepartment of Materials, Department of Bioengineering and Institute for Biomedical Engineering, Imperial College London, London, SW7 2AZ, UK.

Funding

British Heart Foundation RE/08/002/23906European Research Council 616417
6 · The paper itself

Abstract

Inspired by biological systems, many biomimetic methods suggest fabrication of functional materials with unique physicochemical properties. Such methods frequently generate organic-inorganic composites that feature highly ordered hierarchical structures with intriguing properties, distinct from their individual components. A striking example is that of DNA-inorganic hybrid micro/nanostructures, fabricated by the rolling circle technique. Here, a novel concept for the encapsulation of bioactive proteins in DNA flowers (DNF) while maintaining the activity of protein payloads is reported. A wide range of proteins, including enzymes, can be simultaneously associated with the growing DNA strands and Mg

Indexed as

DNAFlowersNanostructuresProteinsDNAProteinscytotoxicityDNA flowersone-pot synthesisprotein deliveryprotein encapsulation

Identifiers

PMID28474844
PMCPMC5516917

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.