Evidence map›Paper›PMID 28474797›Full record

ReviewProtein science : a publication of the Protein Society2017

A mechanistic study of helicases with magnetic traps.

Samar Hodeib, Saurabh Raj, Maria Manosas, Weiting Zhang, Debjani Bagchi, Bertrand Ducos, Francesca Fiorini, Joanne Kanaan, Hervé Le Hir, Jean-François Allemand and 2 more

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Protein science : a publication of the Protein Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Sequence-dependent mechanochemical coupling of helicase translocation and unwinding at single-nucleotide resolution.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  2. Review
  3. Review
  4. Article
  5. Approaches for measuring the dynamics of RNA-protein interactions.Wiley interdisciplinary reviews. RNA · 2020
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 3 countries.

Samar HodeibLaboratoire de physique statistique, Département de physique de l'ENS, École normale supérieure, PSL Research University, Université Paris Diderot, Sorbonne Paris Cité, Sorbonne Universités, UPMC Univ. Paris 06, CNRS, 75005, Paris, France.
Saurabh RajLaboratoire de physique statistique, Département de physique de l'ENS, École normale supérieure, PSL Research University, Université Paris Diderot, Sorbonne Paris Cité, Sorbonne Universités, UPMC Univ. Paris 06, CNRS, 75005, Paris, France.
Maria ManosasDepartament de Física Fonamental, Facultat de Física, Universitat de Barcelona, Barcelona, 08028, Spain.
Weiting ZhangLaboratoire de physique statistique, Département de physique de l'ENS, École normale supérieure, PSL Research University, Université Paris Diderot, Sorbonne Paris Cité, Sorbonne Universités, UPMC Univ. Paris 06, CNRS, 75005, Paris, France.
Debjani BagchiLaboratoire de physique statistique, Département de physique de l'ENS, École normale supérieure, PSL Research University, Université Paris Diderot, Sorbonne Paris Cité, Sorbonne Universités, UPMC Univ. Paris 06, CNRS, 75005, Paris, France.
Bertrand DucosLaboratoire de physique statistique, Département de physique de l'ENS, École normale supérieure, PSL Research University, Université Paris Diderot, Sorbonne Paris Cité, Sorbonne Universités, UPMC Univ. Paris 06, CNRS, 75005, Paris, France.
Francesca FioriniUniv Lyon, Molecular Microbiology and Structural Biochemistry, MMSB-IBCP UMR5086 CNRS/Lyon1, Lyon Cedex 7, 69367, France.
Joanne KanaanInstitut de Biologie de l'Ecole Normale Supérieure (IBENS), Département de biologie, École normale supérieure, CNRS, INSERM, PSL Research University, 75005, Paris, France.
Hervé Le HirInstitut de Biologie de l'Ecole Normale Supérieure (IBENS), Département de biologie, École normale supérieure, CNRS, INSERM, PSL Research University, 75005, Paris, France.
Jean-François AllemandLaboratoire de physique statistique, Département de physique de l'ENS, École normale supérieure, PSL Research University, Université Paris Diderot, Sorbonne Paris Cité, Sorbonne Universités, UPMC Univ. Paris 06, CNRS, 75005, Paris, France.
David BensimonLaboratoire de physique statistique, Département de physique de l'ENS, École normale supérieure, PSL Research University, Université Paris Diderot, Sorbonne Paris Cité, Sorbonne Universités, UPMC Univ. Paris 06, CNRS, 75005, Paris, France.
Vincent CroquetteLaboratoire de physique statistique, Département de physique de l'ENS, École normale supérieure, PSL Research University, Université Paris Diderot, Sorbonne Paris Cité, Sorbonne Universités, UPMC Univ. Paris 06, CNRS, 75005, Paris, France.
Inserm · FRUniversité Paris Cité · FRBiomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine · ESCentre National de la Recherche Scientifique · FRInstitut de Biologie de l'École Normale Supérieure · FRSorbonne Université · FRStructural and Molecular Basis of Infectious Systems · FRUniversité Paris Sciences et Lettres · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicases are a broad family of enzymes that separate nucleic acid double strand structures (DNA/DNA, DNA/RNA, or RNA/RNA) and thus are essential to DNA replication and the maintenance of nucleic acid integrity. We review the picture that has emerged from single molecule studies of the mechanisms of DNA and RNA helicases and their interactions with other proteins. Many features have been uncovered by these studies that were obscured by bulk studies, such as DNA strands switching, mechanical (rather than biochemical) coupling between helicases and polymerases, helicase-induced re-hybridization and stalled fork rescue.

Indexed as

DNADNA HelicasesNucleic Acid HeteroduplexesRNA, Double-StrandedRNA HelicasesDNA ReplicationDNADNA HelicasesNucleic Acid HeteroduplexesRNA, Double-StrandedRNA Helicasesactive unwindingDNA unwindingds-DNA forkfork regressionhelicase/polymerase couplinghelicasesHolliday junction migrationmagnetic trapspolymeraseprimaseprimosomereplisomestrand annealing

Identifiers

PMID28474797
PMCPMC5477542
OpenAlexW2611646612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.