Evidence map›Paper›PMID 28474577›Full record

ArticleBioMedicine2017

Association of inflammatory cytokines with mortality in peritoneal dialysis patients.

Yao-Lung Liu, Jiung-Hsiun Liu, I-Kuan Wang, Shu-Woei Ju, Tung-Min Yu, I-Ru Chen, Yu-Ching Liu, Chung-Ming Huang, Shih-Yi Lin, Chiz-Tzung Chang and 1 more

Open access · diamondAbstract read
In one paragraph

Article in BioMedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yao-Lung LiuGraduate Institute of Clinical Medical Science, China Medical University College of Medicine, Taichung 404, Taiwan - Department of Internal Medicine, China Medical University College of Medicine, Taichung 404, Taiwan - Division of Nephrology, China Medical University Hospital, Taichung 404, Taiwan.
Jiung-Hsiun LiuGraduate Institute of Clinical Medical Science, China Medical University College of Medicine, Taichung 404, Taiwan - Department of Internal Medicine, China Medical University College of Medicine, Taichung 404, Taiwan - Division of Nephrology, China Medical University Hospital, Taichung 404, Taiwan.
I-Kuan WangGraduate Institute of Clinical Medical Science, China Medical University College of Medicine, Taichung 404, Taiwan - Department of Internal Medicine, China Medical University College of Medicine, Taichung 404, Taiwan - Division of Nephrology, China Medical University Hospital, Taichung 404, Taiwan.
Shu-Woei JuDepartment of Internal Medicine, China Medical University College of Medicine, Taichung 404, Taiwan - Division of Nephrology, China Medical University Hospital, Taichung 404, Taiwan.
Tung-Min YuGraduate Institute of Clinical Medical Science, China Medical University College of Medicine, Taichung 404, Taiwan - Division of Nephrology, Taichung Veteran General Hospital, Taichung 407, Taiwan.
I-Ru ChenDepartment of Internal Medicine, China Medical University College of Medicine, Taichung 404, Taiwan - Division of Nephrology, China Medical University Hospital, Taichung 404, Taiwan.
Yu-Ching LiuDepartment of Medical Research, China Medical University Hospital, Taichung 404, Taiwan.
Chung-Ming HuangDivision of Immunology and Rheumatology, China Medical University Hospital, Taichung 404, Taiwan - Graduate Institute of Integrated Medicine, China Medical University, Taichung 404, Taiwan.
Shih-Yi LinGraduate Institute of Clinical Medical Science, China Medical University College of Medicine, Taichung 404, Taiwan - Department of Internal Medicine, China Medical University College of Medicine, Taichung 404, Taiwan - Division of Nephrology, China Medical University Hospital, Taichung 404, Taiwan.
Chiz-Tzung ChangGraduate Institute of Clinical Medical Science, China Medical University College of Medicine, Taichung 404, Taiwan - Department of Internal Medicine, China Medical University College of Medicine, Taichung 404, Taiwan - Division of Nephrology, China Medical University Hospital, Taichung 404, Taiwan.
Chiu-Ching HuangGraduate Institute of Clinical Medical Science, China Medical University College of Medicine, Taichung 404, Taiwan - Department of Internal Medicine, China Medical University College of Medicine, Taichung 404, Taiwan - Division of Nephrology, China Medical University Hospital, Taichung 404, Taiwan.
China Medical University · TWChina Medical University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsPrevious study on association between pro-inflammatory cytokines and mortality in PD population is limited. We aimed to investigate here.

methodsTotal 50 patients who underwent incident PD were enrolled in this study. We measured the titers of pro-inflammatory cytokines Interleukin-18(IL-18), Interleukin-6 (IL-6), and Interleukin-1ß (IL-1ß). Study outcomes were all-cause mortality, cardiovascular-related mortality, and infection-caused mortality. Cox-regression model was used.

resultsIn this 7 year prospective study, IL-18 ≥ 804.3pg/ml, IL-6 ≥ 3.92 pg/ml, IL-1ß ≥ 0.86pg/ml, age ≥ 50 years-old, and existence of diabetes could be used as individual significant predictors for mortality in PD patients. Higher titers of IL-6 were associated with lower averaging albumin levels within 1

conclusionAge ≥ 50 years-old, diabetes, and inflammatory cytokines profiles at the start of PD therapy could predict for 7-year mortality in PD population.

Identifiers

PMID28474577
PMCPMC5439334
OpenAlexW2591993572

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.