Evidence map›Paper›PMID 28474192›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2018

Dual-time-point FDG PET/CT imaging in prosthetic heart valve endocarditis.

A M Scholtens, L E Swart, H J Verberne, R P J Budde, M G E H Lam

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  4. Review
  5. Current cardiology reports · 2021
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Another potential step to improve prosthetic heart valve endocarditis imaging withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  11. Recommendations on nuclear and multimodality imaging in IE and CIED infections.European journal of nuclear medicine and molecular imaging · 2018
    Article
  12. FDG PET/CT in prosthetic heart valve endocarditis: There is no need to wait.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

A M ScholtensDepartment of Nuclear Medicine, Meander Medical Center, Maatweg 3, 3813TZ, Amersfoort, The Netherlands. a.scholtens@meandermc.nl.
L E SwartDepartment of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
H J VerberneDepartment of Radiology and Nuclear Medicine, Academic Medical Center, Amsterdam, The Netherlands.
R P J BuddeDepartment of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
M G E H LamDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Erasmus MC · NLAcademic Medical Center · NLMeander Medisch Centrum · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFDG PET/CT has been of increasing interest in the diagnostic workup of prosthetic heart valve endocarditis (PVE). Some reports advocate later imaging time points to improve the diagnostic accuracy for PVE. In this study, we compared standard and late FDG PET/CT images in patients with a clinical suspicion of PVE. MATERIALS AND

methodsFourteen scans in 13 patients referred for FDG PET/CT for suspicion of PVE performed at standard (60 min post injection) and late (150 min post injection) time points were scored based on visual interpretation and semi-quantitatively with SUVmax and target-to-background ratio (TBR, defined as [SUVmax valve/SUVmean blood pool]). Final diagnosis was based on surgical findings in all cases of infection (n = 6) and unremarkable follow-up in all others (n = 8).

resultsLate images were more prone to false positive interpretation for both visual and semi-quantitative analyses. Visual analysis of the standard images yielded 1 false negative and 1 false positive result. On the late images, no scans were false negative but 5 scans were false positive.

conclusionLate FDG PET/CT imaging for PVE seems prone to false positive results. Therefore, late imaging should be interpreted with caution.

Indexed as

Fluorodeoxyglucose F18RadiopharmaceuticalsAdultAgedAged, 80 and overEndocarditis, BacterialHeart Valve Prosthesis ImplantationHumansMiddle AgedPositron Emission Tomography Computed TomographyProsthesis-Related InfectionsFluorodeoxyglucose F18RadiopharmaceuticalsendocarditisFDG PET/CTprosthetic heart valve

Identifiers

PMID28474192
PMCPMC6280957
OpenAlexW2611417930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.