Evidence map›Paper›PMID 28474046›Full record

ReviewMetallomics : integrated biometal science2017

Mechanistic insight into the heme-independent interplay between iron and carbon monoxide in CFTR and Slo1 BK

Guangyu Wang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Metallomics : integrated biometal science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Guangyu WangDepartment of Physiology and Membrane Biology, University of California School of Medicine, Davis, CA, USA. gary.wang10@gmail.com and Institute of Biophysical Medico-chemistry, Reno, NV, USA.ORCID 0000-0002-5581-6926
University of California, Davis · US

Funding

Alcohol Tissue InjuryT32AA007463 · NIAAA · THOMAS JEFFERSON UNIVERSITY · PI HOEK, JOANNES B, VADIGEPALLI, RAJANIKANTH · 1985 to 2021
$9.1M
Regulation of Neuronal Excitability (P01)P01NS037444 · NINDS · UNIVERSITY OF TEXAS AUSTIN · PI JOHNSTON, DANIEL · 1999 to 2008
$8.4M
MOLECULAR PROPERTIES OF SUBTHRESHOLD POTASSIUM CHANNELSR01NS032337 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI COVARRUBIAS, MANUEL L · 1999 to 2010
$2.8M
New paradigms of CFTR regulationR56DK056796 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIRK, KEVIN L · 2010 to 2010
$220k
NIAAA NIH HHS T32 AA007463NIDDK NIH HHS R56 DK056796NINDS NIH HHS P01 NS037444NINDS NIH HHS R01 NS032337
6 · The paper itself

Abstract

Ion channels have been extensively reported as effectors of carbon monoxide (CO). However, the mechanisms of heme-independent CO action are still not known. Because most ion channels are heterologously expressed on human embryonic kidney cells that are cultured in Fe

Indexed as

Carbon MonoxideCell MembraneCystic Fibrosis Transmembrane Conductance RegulatorHemeHumansIon Channel GatingIronLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsProtein BindingCarbon MonoxideCFTR protein, humanCystic Fibrosis Transmembrane Conductance RegulatorHemeIronKCNMA1 protein, humanLarge-Conductance Calcium-Activated Potassium Channel alpha Subunits

Identifiers

PMID28474046
PMCPMC5505623
OpenAlexW2606102833

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.