Evidence map›Paper›PMID 28474031›Full record

ArticleChemical communications (Cambridge, England)2017

Stimulated Raman scattering of polymer nanoparticles for multiplexed live-cell imaging.

Fanghao Hu, Spencer D Brucks, Tristan H Lambert, Luis M Campos, Wei Min

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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  8. Single-particle imaging of nanomedicine entering the brain.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Advances in stimulated Raman scattering imaging for tissues and animals.Quantitative imaging in medicine and surgery · 2021
    Review
  16. Frontiers in bioengineering and biotechnology · 2020
    Review
  17. Article
  18. Review
  19. Stimulated Raman Excited Fluorescence Spectroscopy of Visible Dyes.The journal of physical chemistry letters · 2019
    Article
  20. Raman Imaging of Nanocarriers for Drug Delivery.Nanomaterials (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fanghao HuDepartment of Chemistry, Columbia University, 3000 Broadway, New York, NY 10027, USA. lcampos@columbia.edu wm2256@columbia.edu.
Spencer D Brucks
Tristan H Lambert
Luis M Campos
Wei Min

Funding

Label-Free Chemical Imaging for Biological ApplicationsDP2EB016573 · NIBIB · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI MIN, WEI · 2012 to 2012
$2.4M
Optical imaging of small bio-molecules in living cells and tissues by nonlinear Raman microscopy coupled with vibrational tagsR01EB020892 · NIBIB · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI MIN, WEI · 2015 to 2018
$1.3M
NIBIB NIH HHS DP2 EB016573NIBIB NIH HHS R01 EB020892
6 · The paper itself

Abstract

A novel nanoparticle-based imaging strategy is introduced that couples biocompatible organic nanoparticles and stimulated Raman scattering (SRS) microscopy. Polymer nanoparticles with vibrational labels incorporated were readily prepared for multi-color SRS imaging with excellent photo-stability. The Raman-active polymer dots are nontoxic, rapidly enter various cell types, and are applied in multiplexed cell-type sorting.

Indexed as

AnimalsChlorocebus aethiopsCOS CellsHeLa CellsHumansMicroscopyNanoparticlesPolymersSpectrum Analysis, RamanPolymers

Identifiers

PMID28474031
PMCPMC5623589

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.