Evidence map›Paper›PMID 28473981›Full record

ArticleBioMed research international2017

Screening of Tumor Suppressor Genes in Metastatic Colorectal Cancer.

Lu Qi, Yanqing Ding

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. A co-regulatory network ofAmerican journal of cancer research · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Lu QiDepartment of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.ORCID 0000-0002-2490-9708
Yanqing DingDepartment of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.ORCID 0000-0002-5988-5064
Nanfang Hospital · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most tumor suppressor genes are commonly inactivated in the development of colorectal cancer (CRC). The activation of tumor suppressor genes may be beneficial to suppress the development and metastasis of CRC. This study analyzed genes expression and methylation levels in different stages of CRC. Genes with downregulated mRNA expression and upregulated methylation level in advanced CRC were screened as the potential tumor suppressor genes. After comparing the methylation level of screened genes, we found that

Indexed as

AgedBinding SitesChromosomes, Human, Pair 17Colorectal NeoplasmsDNA-Binding ProteinsDNA MethylationFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedNeoplasm MetastasisSp1 Transcription FactorTranscription FactorsTumor Suppressor ProteinsDNA-Binding ProteinsMBD1 protein, humanSP1 protein, humanSp1 Transcription FactorTranscription FactorsTumor Suppressor Proteins

Identifiers

PMID28473981
PMCPMC5394352
OpenAlexW2605183923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.