Evidence map›Paper›PMID 28473966›Full record

ArticleFrontiers in cellular and infection microbiology2017

Investigation of

Xuwu Xiang, Youyun Yang, Jimei Du, Tianyu Lin, Tong Chen, X Frank Yang, Yongliang Lou

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Infection and immunity · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. AnInfection and immunity · 2021
    Article
  11. Article
  12. Review
  13. Article
  14. Human and Veterinary Vaccines for Lyme Disease.Current issues in molecular biology · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Role of HK2 in the Enzootic Cycle ofFrontiers in medicine · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Xuwu XiangKey Laboratory of Laboratory Medicine, Ministry of Education of China, School of Laboratory Medicine, Wenzhou Medical UniversityWenzhou, China.
Youyun YangDepartment of Microbiology and Immunology, Indiana University School of MedicineIndianapolis, IN, USA.
Jimei DuKey Laboratory of Laboratory Medicine, Ministry of Education of China, School of Laboratory Medicine, Wenzhou Medical UniversityWenzhou, China.
Tianyu LinCollege of Arts and Sciences, University of PennsylvaniaPhiladelphia, PA, USA.
Tong ChenKey Laboratory of Laboratory Medicine, Ministry of Education of China, School of Laboratory Medicine, Wenzhou Medical UniversityWenzhou, China.
X Frank YangKey Laboratory of Laboratory Medicine, Ministry of Education of China, School of Laboratory Medicine, Wenzhou Medical UniversityWenzhou, China.
Yongliang LouKey Laboratory of Laboratory Medicine, Ministry of Education of China, School of Laboratory Medicine, Wenzhou Medical UniversityWenzhou, China.
Wenzhou Medical University · CNIndiana University School of MedicineIndiana University – Purdue University Indianapolis · USUniversity of the Sciences · US

Funding

Regulatory Network of the Lyme Disease PathogenR01AI083640 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI X. Frank Yang · 2009 to 2026
$5.9M
EXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR015481 · NCRR · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI FIFE, ROSE S · 2001 to 2001
$1.6M
Cyclic di-GMP-dependent regulation of metabolism and virulence in Borrelia burgdorferiR21AI117198 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI GOMELSKY, MARK, YANG, X. FRANK · 2015 to 2016
$429k
The mechanism of activation of the Rrp2-RpoN-RpoS pathway in Borrelia burgdorferiR21AI085242 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI YANG, X. FRANK · 2010 to 2011
$397k
NCRR NIH HHS C06 RR015481NIAID NIH HHS R01 AI083640NIAID NIH HHS R21 AI085242NIAID NIH HHS R21 AI117198
6 · The paper itself

Abstract

Outer surface protein C (OspC) is the most studied major virulence factor of

Indexed as

Gene Expression Regulation, BacterialAntigens, BacterialBacterial Outer Membrane ProteinsBacterial ProteinsBorrelia burgdorferiDNA, BacterialDNA PrimersGene Expression ProfilingGenes, BacterialLyme DiseaseMultiplex Polymerase Chain ReactionPhenotypePlasmidsAntigens, BacterialBacterial Outer Membrane ProteinsBacterial ProteinsDNA, BacterialDNA PrimersOspC proteinBorrelia burgdorferiBosRendogenous plasmidmultiplex PCROspC

Identifiers

PMID28473966
PMCPMC5397415
OpenAlexW2609900495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.