Evidence map›Paper›PMID 28473879›Full record

ArticleOxidative medicine and cellular longevity2017

Dihydropyridine Derivatives as Cell Growth Modulators In Vitro.

Imanta Bruvere, Egils Bisenieks, Janis Poikans, Janis Uldrikis, Aiva Plotniece, Karlis Pajuste, Martins Rucins, Brigita Vigante, Zenta Kalme, Marina Gosteva and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. 1,4-dihydropyridine derivatives increase mRNA expression ofArhiv za higijenu rada i toksikologiju · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 3 countries.

Imanta BruvereLatvian Institute of Organic Synthesis, 21 Aizkraukles Str., Riga LV-1006, Latvia.
Egils BisenieksLatvian Institute of Organic Synthesis, 21 Aizkraukles Str., Riga LV-1006, Latvia.
Janis PoikansLatvian Institute of Organic Synthesis, 21 Aizkraukles Str., Riga LV-1006, Latvia.ORCID 0000-0003-2933-7507
Janis UldrikisLatvian Institute of Organic Synthesis, 21 Aizkraukles Str., Riga LV-1006, Latvia.
Aiva PlotnieceLatvian Institute of Organic Synthesis, 21 Aizkraukles Str., Riga LV-1006, Latvia.
Karlis PajusteLatvian Institute of Organic Synthesis, 21 Aizkraukles Str., Riga LV-1006, Latvia.
Martins RucinsLatvian Institute of Organic Synthesis, 21 Aizkraukles Str., Riga LV-1006, Latvia.
Brigita ViganteLatvian Institute of Organic Synthesis, 21 Aizkraukles Str., Riga LV-1006, Latvia.
Zenta KalmeLatvian Institute of Organic Synthesis, 21 Aizkraukles Str., Riga LV-1006, Latvia.
Marina GostevaLatvian Institute of Organic Synthesis, 21 Aizkraukles Str., Riga LV-1006, Latvia.
Ilona DomrachevaLatvian Institute of Organic Synthesis, 21 Aizkraukles Str., Riga LV-1006, Latvia.
Astrida VelenaLatvian Institute of Organic Synthesis, 21 Aizkraukles Str., Riga LV-1006, Latvia.ORCID 0000-0003-1392-1936
Tea VukovicLaboratory for Oxidative Stress, Rudjer Boskovic Institute, Bijenicka 54, 10000 Zagreb, Croatia.
Lidija MilkovicLaboratory for Oxidative Stress, Rudjer Boskovic Institute, Bijenicka 54, 10000 Zagreb, Croatia.
Gunars DubursLatvian Institute of Organic Synthesis, 21 Aizkraukles Str., Riga LV-1006, Latvia.ORCID 0000-0002-3071-6056
Neven ZarkovicLaboratory for Oxidative Stress, Rudjer Boskovic Institute, Bijenicka 54, 10000 Zagreb, Croatia.ORCID 0000-0001-5032-0369
Latvijas Organiskās Sintēzes Institūts · LVRuđer Bošković Institute · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of eleven 1,4-dihydropyridine derivatives (DHPs) used alone or together with prooxidant anticancer drug doxorubicin were examined on two cancer (HOS, HeLa) and two nonmalignant cell lines (HMEC, L929). Their effects on the cell growth (

Indexed as

DihydropyridinesFree Radical ScavengersAnimalsDose-Response Relationship, DrugDoxorubicinDrug Screening Assays, AntitumorHeLa CellsHumansMiceNeoplasmsRatsWound HealingDihydropyridinesDoxorubicinFree Radical Scavengers

Identifiers

PMID28473879
PMCPMC5394904
OpenAlexW2604361851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.