ReviewFrontiers in neurology2017
Cerebrovascular Manifestations of Lyme Neuroborreliosis-A Systematic Review of Published Cases.
Review in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- Varicella-zoster virus vasculopathy: a rare complication of Ramsay Hunt Syndrome: a literature review.Frontiers in neurology · 2025Pooled it
- Cerebrovascular manifestations of herpes simplex virus infection of the central nervous system: a systematic review.Journal of neuroinflammation · 2019Pooled it
- Lyme neuroborreliosis as a cause of acute ischemic stroke: A case report.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Article
- Ischemic stroke and transient ischemic attack associated with neuroborreliosis: a Danish retrospective cohort.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Findings on Magnetic Resonance Imaging in Neuroborreliosis-A Nationwide Cohort Study.European journal of neurology · 2026Article
- Peripheral Facial Paralysis as a Sentinel Symptom of Early Lyme Neuroborreliosis: A Diagnostic Challenge.Cureus · 2025Article
- Stroke, infections, and New Mechanisms: a Narrative Review.Current neurology and neuroscience reports · 2025Review
- Case report of ischemic stroke in a child secondary to neuroborreliosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Borrelia burgdorferi: A Rare Cause of Stroke.Cureus · 2025Article
- Multiple Severe Intracranial Stenoses with Ischemic Stroke in Neuroborreliosis-associated Cerebral Vasculitis: Endovascular Treatment Strategies and Literature Review.Clinical neuroradiology · 2024Review
- Central nervous system manifestations in rheumatic diseases.Rheumatology international · 2024Review
- [Inflammatory causes of stroke-Diagnostics and treatment].Der Nervenarzt · 2024Article
- The case of a 38-year-old man with transient right arm weakness and dysarthria.Annals of clinical and translational neurology · 2024Article
- Spectrum of MRI findings in central nervous system affection in Lyme neuroborreliosis.Scientific reports · 2024Article
- Seroprevalence of Toxoplasma gondii and Borrelia burgdorferi infections in patients with multiple sclerosis in Poland.Scientific reports · 2024Article
- Clinical and epidemiological features of Lyme neuroborreliosis in adults and factors associated with polyradiculitis, facial palsy and encephalitis or myelitis.Scientific reports · 2023Article
- Vasculitis and Ischemic Stroke in Lyme Neuroborreliosis-Interventional Management Approach and Literature Review.Brain sciences · 2023Review
- A Longitudinal Study of a Large Clinical Cohort of Patients with Lyme Disease and Tick-Borne Co-Infections Treated with Combination Antibiotics.Microorganisms · 2023Article
- Lyme radiculopathy in a septuagenarian.BMJ case reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLyme neuroborreliosis (LNB) is a disease caused by spirochete MATERIALS AND
methodsWe conducted a systematic review of literature between May 1987 and December 2016 with patients who presented with cerebrovascular course of LNB.
resultsThis study included 88 patients with a median age of 46 years. The median interval from onset of symptoms suggesting Lyme disease to first symptoms of cerebrovascular manifestations of LNB was 3.5 months. The most common cerebrovascular manifestation of LNB was ischemic stroke (76.1%), followed by TIA (11.4%). The posterior circulation was affected alone in 37.8% of patients, the anterior circulation in 24.4% of patients, and in 37.8% of cases, posterior and anterior circulations were affected simultaneously. The most common affected vessels were middle cerebral artery-in 19 cases, basilar artery-in 17 cases, and anterior cerebral artery-in 16 cases. A good response to antibiotic treatment was achieved in the vast number of patients (75.3%). The overall mortality rate was 4.7%.
conclusionCerebral vasculitis and stroke due to LNB should be considered, especially in patients who live in or have come from areas with high prevalence of tick-borne diseases, as well as in those without cardiovascular risk factors, but with stroke-like symptoms of unknown cause.
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