Evidence map›Paper›PMID 28473458›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2017

Effects of Acute and Chronic Treatments with Dopamine D

Morgane Thomsen, Andrew C Barrett, Paul Butler, S Stevens Negus, S Barak Caine

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Medications Development for Treatment of Opioid Use Disorder.Cold Spring Harbor perspectives in medicine · 2021
    Review
  14. (±)VK4-40, a novel dopamine DBritish journal of pharmacology · 2020
    Article
  15. Article
  16. Review
  17. The highly selective dopamine DNeuropharmacology · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Morgane ThomsenAlcohol and Drug Abuse Research Center, McLean Hospital, Belmont, Massachusetts (M.T., A.C.B., S.B.C.); Department of Psychiatry, Harvard Medical School, Belmont, Massachusetts (M.T., A.C.B., S.B.C.); Laboratory of Neuropsychiatry, Psychiatric Centre Copenhagen, University of Copenhagen, Copenhagen, Denmark (M.T.); Drug Safety Research and Development, Pfizer, San Diego, California (P.B.); and Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia (S.S.N.) mthomsen@mclean.harvard.edu.
Andrew C BarrettAlcohol and Drug Abuse Research Center, McLean Hospital, Belmont, Massachusetts (M.T., A.C.B., S.B.C.); Department of Psychiatry, Harvard Medical School, Belmont, Massachusetts (M.T., A.C.B., S.B.C.); Laboratory of Neuropsychiatry, Psychiatric Centre Copenhagen, University of Copenhagen, Copenhagen, Denmark (M.T.); Drug Safety Research and Development, Pfizer, San Diego, California (P.B.); and Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia (S.S.N.).
Paul ButlerAlcohol and Drug Abuse Research Center, McLean Hospital, Belmont, Massachusetts (M.T., A.C.B., S.B.C.); Department of Psychiatry, Harvard Medical School, Belmont, Massachusetts (M.T., A.C.B., S.B.C.); Laboratory of Neuropsychiatry, Psychiatric Centre Copenhagen, University of Copenhagen, Copenhagen, Denmark (M.T.); Drug Safety Research and Development, Pfizer, San Diego, California (P.B.); and Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia (S.S.N.).
S Stevens NegusAlcohol and Drug Abuse Research Center, McLean Hospital, Belmont, Massachusetts (M.T., A.C.B., S.B.C.); Department of Psychiatry, Harvard Medical School, Belmont, Massachusetts (M.T., A.C.B., S.B.C.); Laboratory of Neuropsychiatry, Psychiatric Centre Copenhagen, University of Copenhagen, Copenhagen, Denmark (M.T.); Drug Safety Research and Development, Pfizer, San Diego, California (P.B.); and Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia (S.S.N.).
S Barak CaineAlcohol and Drug Abuse Research Center, McLean Hospital, Belmont, Massachusetts (M.T., A.C.B., S.B.C.); Department of Psychiatry, Harvard Medical School, Belmont, Massachusetts (M.T., A.C.B., S.B.C.); Laboratory of Neuropsychiatry, Psychiatric Centre Copenhagen, University of Copenhagen, Copenhagen, Denmark (M.T.); Drug Safety Research and Development, Pfizer, San Diego, California (P.B.); and Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia (S.S.N.).
McLean Hospital · USUniversity of Copenhagen · DKHarvard University · US

Funding

Medications Development for Stimulant AbuseR01DA026946 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI NEGUS, SIDNEY S · 2009 to 2019
$3.7M
DRUG ABUSE RESEARCH TRAINING PROGRAMT32DA007252 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI MELLO, NANCY K. · 1991 to 2011
$3.0M
Selective Muscarinic Receptor Ligands as Targets for Cocaine Addiction MedicationR00DA027825 · NIDA · MCLEAN HOSPITAL · PI THOMSEN, MORGANE HERMANN · 2012 to 2014
$710k
COCAINE SELF ADMINISTRATION IN DOPAMINE KNOCKOUT MICER29DA012142 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI CAINE, SIMON BARAK · 1999 to 2003
$414k
NIDA NIH HHS R00 DA027825NIDA NIH HHS R01 DA026946NIDA NIH HHS R29 DA012142NIDA NIH HHS T32 DA007252
6 · The paper itself

Abstract

Dopamine D

Indexed as

FoodAminopyridinesAnimalsBenzamidesChoice BehaviorCocaineConditioning, OperantDopamine AgonistsDopamine AntagonistsDopamine D2 Receptor AntagonistsDose-Response Relationship, DrugDrug ToleranceIndolesLigandsMaleMorpholines3-(4-(4-chlorophenyl-4-hydroxypiperidino)methyl)indoleAminopyridinesBenzamidesCocaineDopamine AgonistsDopamine AntagonistsDopamine D2 Receptor AntagonistsDRD2 protein, ratDrd3 protein, ratIndolesLigandsMorpholinesN-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)but-2-enyl)-4-pyridine-2-ylbenzamidePF 592379PiperidinesPyridinesReceptors, Dopamine D2Receptors, Dopamine D3

Identifiers

PMID28473458
PMCPMC5469403
OpenAlexW2611268510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.