Evidence map›Paper›PMID 28473330›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2017

CD44

Qian Chen, Varsha Suresh Kumar, Johanna Finn, Dianhua Jiang, Jiurong Liang, You-Yang Zhao, Yuru Liu

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Cellular plasticity and regenerative mechanisms in the lung.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  4. Single-Cell Insights Into Macrophage Subtypes in Pulmonary Infections.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  5. Article
  6. Journal of respiratory biology and translational medicine · 2025
    Article
  7. Article
  8. Review
  9. Recruited atypical Ly6GScience immunology · 2024
    Article
  10. Article
  11. Arrestin beta 1 Regulates Alveolar Progenitor Renewal and Lung Fibrosis.Journal of respiratory biology and translational medicine · 2024
    Article
  12. Epithelial stem cells and niches in lung alveolar regeneration and diseases.Chinese medical journal pulmonary and critical care medicine · 2024
    Article
  13. Article
  14. Rational engineering of lung alveolar epithelium.NPJ Regenerative medicine · 2023
    Article
  15. The Regenerative Power of Stem Cells: Treating Bleomycin-Induced Lung Fibrosis.Stem cells and cloning : advances and applications · 2023
    Review
  16. Lung Regeneration: Cells, Models, and Mechanisms.Cold Spring Harbor perspectives in biology · 2022
    Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Qian ChenDepartment of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois; and.
Varsha Suresh KumarDepartment of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois; and.
Johanna FinnDepartment of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois; and.
Dianhua JiangDivision of Pulmonary and Critical Care Medicine, Cedars-Sinai Medical Center, Los Angeles, California.
Jiurong LiangDivision of Pulmonary and Critical Care Medicine, Cedars-Sinai Medical Center, Los Angeles, California.
You-Yang ZhaoDepartment of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois; and.
Yuru LiuDepartment of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois; and yuruliu@uic.edu.
University of Illinois Urbana-Champaign · USCedars-Sinai Medical Center · USIllinois College · USUniversity of Illinois Chicago · US

Funding

Trpm2 Regulation of Phagocyte Bactericidal Activity and Resolution of Lung InjuryP01HL077806 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ZHAO, YOU-YANG · 2005 to 2019
$27.0M
TRAINING PROGRAM IN LUNG BIOLOGY AND PATHOBIOLOGYT32HL007829 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DOLLY MEHTA · 1995 to 2026
$15.6M
Regulation of type II cells in the repair of alveolar epithelial injuryR01HL105947 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YURU LIU · 2012 to 2026
$5.7M
Novel mechanisms of obliterative pulmonary vascular remodeling and sever pulmonary arterial hypertensionR01HL133951 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ZHAO, YOU-YANG · 2016 to 2024
$4.9M
Repair mechanisms of sepsis induced endothelial dysfunction and lung injuryR01HL125350 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MALIK, ASRAR B., ZHAO, YOU-YANG · 2014 to 2018
$3.2M
Novel Signalings and Molecular Targets Of Endothelial Regeneration In Aging LungR01HL123957 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ZHAO, YOU-YANG · 2014 to 2018
$2.0M
NHLBI NIH HHS P01 HL077806NHLBI NIH HHS R01 HL105947NHLBI NIH HHS R01 HL125350NHLBI NIH HHS R01 HL133951NHLBI NIH HHS T32 HL007829
6 · The paper itself

Abstract

The alveolar epithelium is composed of type I cells covering most of the gas-blood exchange surface and type II cells secreting surfactant that lowers surface tension of alveoli to prevent alveolar collapse. Here, we have identified a subgroup of type II cells expressing a higher level of cell surface molecule CD44 (CD44

Indexed as

HomeostasisAgingAlveolar Epithelial CellsAnimalsCapillariesCell DifferentiationCell LineageCell ProliferationCells, CulturedHyaluronan ReceptorsIntegrinsLungMice, Inbred C57BLOrganoidsPulmonary Surfactant-Associated Protein CStem CellsHyaluronan ReceptorsIntegrinsPulmonary Surfactant-Associated Protein CalveoliCD44homeostasislungtype II cells

Identifiers

PMID28473330
PMCPMC5538873
OpenAlexW2610740349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.